%0 Journal Article %1 barton1979geneflow %A Barton, NH %D 1979 %I The Genetical Society of Great Britain %J Heredity %K clines diffusion_approximation gene_flow haplotype_length linkage selection spatial_structure %N 3 %P 333--339 %T Gene flow past a cline %U http://dx.doi.org/10.1038/hdy.1979.86 %V 43 %X The effect of a cline as a barrier to gene flow at closely linked, weakly selected loci is investigated using a continuous diffusion model. It is shown that a linked cline induces a step in the frequency of a neutral allele, which is proportional to the gradient in neutral allele frequency and to the inverse of the recombination rate. A barrier to dispersal or a local region of low abundance has a similar effect (Nagylaki, 1976). The cline will block the flow of neutral alleles over a region of chromosome roughly 2 sqrt s/t map units long. However, a slightly advantageous allele will be little affected, and must be very tightly linked to be delayed for long.

@article{barton1979geneflow, abstract = {The effect of a cline as a barrier to gene flow at closely linked, weakly selected loci is investigated using a continuous diffusion model. It is shown that a linked cline induces a step in the frequency of a neutral allele, which is proportional to the gradient in neutral allele frequency and to the inverse of the recombination rate. A barrier to dispersal or a local region of low abundance has a similar effect (Nagylaki, 1976). The cline will block the flow of neutral alleles over a region of chromosome roughly 2 sqrt s/t map units long. However, a slightly advantageous allele will be little affected, and must be very tightly linked to be delayed for long.}, added-at = {2009-01-12T05:24:36.000+0100}, author = {Barton, NH}, biburl = {https://www.bibsonomy.org/bibtex/2508d106f012a2dc8f9eb9df7b9e99fcf/peter.ralph}, description = {Gene flow past a cline}, interhash = {17e5f934300682ab313a4da1df2e8725}, intrahash = {508d106f012a2dc8f9eb9df7b9e99fcf}, issn = {0018-067X}, journal = {Heredity}, keywords = {clines diffusion_approximation gene_flow haplotype_length linkage selection spatial_structure}, month = dec, number = 3, pages = {333--339}, publisher = {The Genetical Society of Great Britain}, timestamp = {2011-04-15T23:00:30.000+0200}, title = {Gene flow past a cline}, url = {http://dx.doi.org/10.1038/hdy.1979.86}, volume = 43, year = 1979 }