%0 Journal Article %1 norberg03a %A Norberg, J %A Nilsson, L. %D 2003 %J Quarterly Reviews of Biophysics %K imported %N 3 %P 257--306 %T Advances in biomolecular simulations: methodology and recent applications %V 36 %X Molecular dynamics simulations are widely used today to tackle problems in biochemistry and molecular biology. In the 25 years since the first simulation of a protein computers have become faster by many orders of magnitude, algorithms and force fields have been improved, and simulations can now be applied to very large systems, such as protein-nucleic acid complexes and multimeric proteins in aqueous solution. In this review we give a general background about molecular dynamics simulations, and then focus on some recent technical advances, with applications to biologically relevant problems.

@article{norberg03a, abstract = {Molecular dynamics simulations are widely used today to tackle problems in biochemistry and molecular biology. In the 25 years since the first simulation of a protein computers have become faster by many orders of magnitude, algorithms and force fields have been improved, and simulations can now be applied to very large systems, such as protein-nucleic acid complexes and multimeric proteins in aqueous solution. In this review we give a general background about molecular dynamics simulations, and then focus on some recent technical advances, with applications to biologically relevant problems.}, added-at = {2007-06-15T17:33:15.000+0200}, author = {Norberg, J and Nilsson, L.}, biburl = {https://www.bibsonomy.org/bibtex/2d6cf6a905b16ac81b5854e6c4da4ffc0/kaigrass}, interhash = {7ebea5c3a97b115919fa44a5c15abf9a}, intrahash = {d6cf6a905b16ac81b5854e6c4da4ffc0}, journal = {Quarterly Reviews of Biophysics}, keywords = {imported}, number = 3, pages = {257--306}, timestamp = {2007-06-15T17:33:22.000+0200}, title = {Advances in biomolecular simulations: methodology and recent applications}, volume = 36, year = 2003 }