Article,

Time-gated biological imaging by use of colloidal quantum dots

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Opt. Lett., 26 (11): 825--827 (June 2001)
DOI: 10.1364/OL.26.000825

Abstract

The long (but not too long) fluorescence lifetime of CdSe semiconductor quantum dots was exploited to enhance fluorescence biological imaging contrast and sensitivity by time-gated detection. Significant and selective reduction of the autofluorescence contribution to the overall image was achieved, and enhancement of the signal-to-background ratio by more than an order of magnitude was demonstrated.

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