Abstract
Ensembl (http://www.ensembl.org/) is a bioinformatics project to organize
biological information around the sequences of large genomes. It
is a comprehensive source of stable automatic annotation of individual
genomes, and of the synteny and orthology relationships between them.
It is also a framework for integration of any biological data that
can be mapped onto features derived from the genomic sequence. Ensembl
is available as an interactive Web site, a set of flat files, and
as a complete, portable open source software system for handling
genomes. All data are provided without restriction, and code is freely
available. Ensembl's aims are to continue to "widen" this biological
integration to include other model organisms relevant to understanding
human biology as they become available; to "deepen" this integration
to provide an ever more seamless linkage between equivalent components
in different species; and to provide further classification of functional
elements in the genome that have been previously elusive.
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