The human recombination activating gene 1 (RAG1) has previously been mapped to chromosomes 14q and 11p. Here we confirm the chromosome 11 assignment by two independent approaches: autoradiographic and fluorescence in situ hybridization to metaphase spreads and analysis of human-hamster somatic cell hybrid DNA by the polymerase chain reaction (PCR) and Southern blotting. Our results unequivocally localize RAG1 to 11p13.
%0 Journal Article
%1 Schwarz.1994
%A Schwarz, K.
%A Hameister, H.
%A Gessler, M.
%A Grzeschik, K. H.
%A Hansen-Hagge, T. E.
%A Bartram, C. R.
%D 1994
%J Hum Genet
%K *Chromosome *Chromosomes;Human;Pair *Genes;RAG-1 11 Animals Autoradiography/methods Base Blotting;Southern CHO Cells Chain Cricetinae DNA Data Humans Hybrid Hybridization;Fluorescence/methods In Mapping Molecular Polymerase Primers/chemistry Reaction Sequence Situ
%N 2
%P 215--217
%T Confirmation of the localization of the human recombination activating gene 1 (RAG1) to chromosome 11p13
%V 93
%X The human recombination activating gene 1 (RAG1) has previously been mapped to chromosomes 14q and 11p. Here we confirm the chromosome 11 assignment by two independent approaches: autoradiographic and fluorescence in situ hybridization to metaphase spreads and analysis of human-hamster somatic cell hybrid DNA by the polymerase chain reaction (PCR) and Southern blotting. Our results unequivocally localize RAG1 to 11p13.
@article{Schwarz.1994,
abstract = {The human recombination activating gene 1 (RAG1) has previously been mapped to chromosomes 14q and 11p. Here we confirm the chromosome 11 assignment by two independent approaches: autoradiographic and fluorescence in situ hybridization to metaphase spreads and analysis of human-hamster somatic cell hybrid DNA by the polymerase chain reaction (PCR) and Southern blotting. Our results unequivocally localize RAG1 to 11p13.},
added-at = {2013-01-29T13:47:26.000+0100},
author = {Schwarz, K. and Hameister, H. and Gessler, M. and Grzeschik, K. H. and Hansen-Hagge, T. E. and Bartram, C. R.},
biburl = {https://www.bibsonomy.org/bibtex/2853355db7f5ec413def1f6931fdd6043/ebch},
interhash = {bda65ec4bc0389b3dc4b711f6b5e05d0},
intrahash = {853355db7f5ec413def1f6931fdd6043},
journal = {Hum Genet},
keywords = {*Chromosome *Chromosomes;Human;Pair *Genes;RAG-1 11 Animals Autoradiography/methods Base Blotting;Southern CHO Cells Chain Cricetinae DNA Data Humans Hybrid Hybridization;Fluorescence/methods In Mapping Molecular Polymerase Primers/chemistry Reaction Sequence Situ},
number = 2,
pages = {215--217},
timestamp = {2013-01-29T13:47:27.000+0100},
title = {Confirmation of the localization of the human recombination activating gene 1 (RAG1) to chromosome 11p13},
volume = 93,
year = 1994
}