The prognosis of heart failure is worse than that of most cancers,
but new therapeutic interventions using stem and other cell-based
therapies are succeeding in the fight against it, and old drugs,
with new twists, are making a comeback. Genetically engineered animal
models are driving insights into the molecular mechanisms that cause
hearts to fail, accelerating drug discoveries, and inspiring cell-based
therapeutic interventions for both acquired and inheritable cardiac
diseases.
%0 Journal Article
%1 Benj_2005_495
%A Benjamin, Ivor J
%A Schneider, Michael D
%D 2005
%J J. Clin. Invest.
%K 15765130 Animals, Apoptosis, Calcium, Congestive, Failure, Gene Genetic, Genetically Genomics, Gov't, Heart Humans, Kinases, Mitochondria, Modified, Nitric Non-U.S. Oxidative Oxide, P.H.S., Protein Research Signal Stress, Support, Therapy, Transcription, Transduction, U.S.
%N 3
%P 495--499
%R 10.1172/JCI200524477
%T Learning from failure: congestive heart failure in the postgenomic
age.
%U http://dx.doi.org/10.1172/JCI200524477
%V 115
%X The prognosis of heart failure is worse than that of most cancers,
but new therapeutic interventions using stem and other cell-based
therapies are succeeding in the fight against it, and old drugs,
with new twists, are making a comeback. Genetically engineered animal
models are driving insights into the molecular mechanisms that cause
hearts to fail, accelerating drug discoveries, and inspiring cell-based
therapeutic interventions for both acquired and inheritable cardiac
diseases.
@article{Benj_2005_495,
abstract = {The prognosis of heart failure is worse than that of most cancers,
but new therapeutic interventions using stem and other cell-based
therapies are succeeding in the fight against it, and old drugs,
with new twists, are making a comeback. Genetically engineered animal
models are driving insights into the molecular mechanisms that cause
hearts to fail, accelerating drug discoveries, and inspiring cell-based
therapeutic interventions for both acquired and inheritable cardiac
diseases.},
added-at = {2009-06-03T11:20:58.000+0200},
author = {Benjamin, Ivor J and Schneider, Michael D},
biburl = {https://www.bibsonomy.org/bibtex/28e6496145056102f97eeb2bcddc4924b/hake},
description = {The whole bibliography file I use.},
doi = {10.1172/JCI200524477},
interhash = {c66aaafccc3486d0369d0110b0881691},
intrahash = {8e6496145056102f97eeb2bcddc4924b},
journal = {J. Clin. Invest.},
keywords = {15765130 Animals, Apoptosis, Calcium, Congestive, Failure, Gene Genetic, Genetically Genomics, Gov't, Heart Humans, Kinases, Mitochondria, Modified, Nitric Non-U.S. Oxidative Oxide, P.H.S., Protein Research Signal Stress, Support, Therapy, Transcription, Transduction, U.S.},
month = Mar,
number = 3,
pages = {495--499},
pmid = {15765130},
timestamp = {2009-06-03T11:21:02.000+0200},
title = {Learning from failure: congestive heart failure in the postgenomic
age.},
url = {http://dx.doi.org/10.1172/JCI200524477},
volume = 115,
year = 2005
}