Detection of gamma-glutamyl transpeptidase (GGT; ggt ) activity is one of the useful methods for a specific identification of Neisseria meningitidis. However, we previously happened to isolate a ggt -deficient N. meningitidis strain (NIID113) from a healthy carrier. In this study, in order to re-examine the reliability of the marker, we again investigated the GGT activity of 245 N. meningitidis human isolates and identified two other GGT-defective N. meningitidis isolates besides NIID113. The isolation frequency (1.2\%) of ggt mutants among human isolates strongly confirmed the 98.8\% reliability of GGT activity as the identification marker for N. meningitidis.
%0 Journal Article
%1 takahashi_reliability_2004
%A Takahashi, Hideyuki
%A Kuroki, Toshiro
%A Watanabe, Yuko
%A Dejsirilert, Surang
%A Saengsuk, Leelaowadee
%A Yamai, Shiro
%A Watanabe, Haruo
%D 2004
%J Microbiology and Immunology
%K Adult, Aged, Bacterial, Carrier Data, Genes, Humans, Infections, Japan, Male, Meningococcal Middle Molecular Mutation, Neisseria Reproducibility Results, Sequence Species Specificity, State, Thailand meningitidis, of {gamma-Glutamyltransferase,}
%N 6
%P 485--487
%T Reliability of the detection of meningococcal gamma-glutamyl transpeptidase as an identification marker for Neisseria meningitidis
%U http://www.ncbi.nlm.nih.gov/pubmed/15215623
%V 48
%X Detection of gamma-glutamyl transpeptidase (GGT; ggt ) activity is one of the useful methods for a specific identification of Neisseria meningitidis. However, we previously happened to isolate a ggt -deficient N. meningitidis strain (NIID113) from a healthy carrier. In this study, in order to re-examine the reliability of the marker, we again investigated the GGT activity of 245 N. meningitidis human isolates and identified two other GGT-defective N. meningitidis isolates besides NIID113. The isolation frequency (1.2\%) of ggt mutants among human isolates strongly confirmed the 98.8\% reliability of GGT activity as the identification marker for N. meningitidis.
@article{takahashi_reliability_2004,
abstract = {Detection of gamma-glutamyl transpeptidase {(GGT;} ggt ) activity is one of the useful methods for a specific identification of Neisseria meningitidis. However, we previously happened to isolate a ggt -deficient N. meningitidis strain {(NIID113)} from a healthy carrier. In this study, in order to re-examine the reliability of the marker, we again investigated the {GGT} activity of 245 N. meningitidis human isolates and identified two other {GGT-defective} N. meningitidis isolates besides {NIID113.} The isolation frequency (1.2\%) of ggt mutants among human isolates strongly confirmed the 98.8\% reliability of {GGT} activity as the identification marker for N. meningitidis.},
added-at = {2011-03-11T10:05:34.000+0100},
author = {Takahashi, Hideyuki and Kuroki, Toshiro and Watanabe, Yuko and Dejsirilert, Surang and Saengsuk, Leelaowadee and Yamai, Shiro and Watanabe, Haruo},
biburl = {https://www.bibsonomy.org/bibtex/212f651abd3123f5afcc930ea9055391a/jelias},
interhash = {0c311e521157d32ab770d87d30b8c3bf},
intrahash = {12f651abd3123f5afcc930ea9055391a},
issn = {0385-5600},
journal = {Microbiology and Immunology},
keywords = {Adult, Aged, Bacterial, Carrier Data, Genes, Humans, Infections, Japan, Male, Meningococcal Middle Molecular Mutation, Neisseria Reproducibility Results, Sequence Species Specificity, State, Thailand meningitidis, of {gamma-Glutamyltransferase,}},
note = {{PMID:} 15215623},
number = 6,
pages = {485--487},
timestamp = {2011-03-11T10:06:39.000+0100},
title = {Reliability of the detection of meningococcal gamma-glutamyl transpeptidase as an identification marker for Neisseria meningitidis},
url = {http://www.ncbi.nlm.nih.gov/pubmed/15215623},
volume = 48,
year = 2004
}