%0 Journal Article %1 Venter2007118 %A Venter, Mauritz %D 2007 %J Trends in Plant Science %K combinatorialregulation synthetic %N 3 %P 118 - 124 %R DOI: 10.1016/j.tplants.2007.01.002 %T Synthetic promoters: genetic control through cis engineering %U http://www.sciencedirect.com/science/article/B6TD1-4N14DD0-1/2/6b991fe54cc41124e9093a1ade11962b %V 12 %X Technological advances in plant genetics integrated with systems biology and bioinformatics has yielded a myriad of novel biological data and insights into plant metabolism. This unprecedented advance has provided a platform for targeted manipulation of transcriptional activity through synthetic promoter engineering, and holds great promise as a way to further our understanding of regulatory complexity. The challenge and strategy for predictive experimental gene expression is the accurate design and use of molecular `switches' and modules that will regulate single or multiple plant transgenes in direct response to specific environmental, physiological and chemical cues. In particular, focusing on cis-motif rearrangement, future plant biotechnology applications and the elucidation of cis- and trans-regulatory mechanisms could greatly benefit from using plant synthetic promoters.

@article{Venter2007118, abstract = {Technological advances in plant genetics integrated with systems biology and bioinformatics has yielded a myriad of novel biological data and insights into plant metabolism. This unprecedented advance has provided a platform for targeted manipulation of transcriptional activity through synthetic promoter engineering, and holds great promise as a way to further our understanding of regulatory complexity. The challenge and strategy for predictive experimental gene expression is the accurate design and use of molecular [`]switches' and modules that will regulate single or multiple plant transgenes in direct response to specific environmental, physiological and chemical cues. In particular, focusing on cis-motif rearrangement, future plant biotechnology applications and the elucidation of cis- and trans-regulatory mechanisms could greatly benefit from using plant synthetic promoters.}, added-at = {2009-06-14T21:03:39.000+0200}, author = {Venter, Mauritz}, biburl = {https://www.bibsonomy.org/bibtex/2200e7abf4068c20246c7a5ea0b162fbd/cchen63}, description = {ScienceDirect - Trends in Plant Science : Synthetic promoters: genetic control through cis engineering}, doi = {DOI: 10.1016/j.tplants.2007.01.002}, interhash = {892c5afd8ec5805b4917739c09c32804}, intrahash = {200e7abf4068c20246c7a5ea0b162fbd}, issn = {1360-1385}, journal = {Trends in Plant Science}, keywords = {combinatorialregulation synthetic}, number = 3, pages = {118 - 124}, timestamp = {2009-06-14T21:03:39.000+0200}, title = {Synthetic promoters: genetic control through cis engineering}, url = {http://www.sciencedirect.com/science/article/B6TD1-4N14DD0-1/2/6b991fe54cc41124e9093a1ade11962b}, volume = 12, year = 2007 }