%0 Journal Article %1 Biro2003408 %A Biro, J. C. %A Benyó, B. %A Sansom, C. %A Szlávecz, Á. %A Fördös, G. %A Micsik, T. %A Benyó, Z. %D 2003 %J Biochemical and Biophysical Research Communications %K Amino_acid Charge Codon Genetic_code Hydrophobicity Nucleic_acid Periodic_table Polarity Protein Translation %N 2 %P 408 - 415 %R DOI: 10.1016/S0006-291X(03)00974-4 %T A common periodic table of codons and amino acids %U http://dx.doi.org/10.1016/S0006-291X(03)00974-4 %V 306 %X A periodic table of codons has been designed where the codons are in regular locations. The table has four fields (16 places in each) one with each of the four nucleotides (A, U, G, C) in the central codon position. Thus, AAA (lysine), UUU (phenylalanine), GGG (glycine), and CCC (proline) were placed into the corners of the fields as the main codons (and amino acids) of the fields. They were connected to each other by six axes. The resulting nucleic acid periodic table showed perfect axial symmetry for codons. The corresponding amino acid table also displaced periodicity regarding the biochemical properties (charge and hydropathy) of the 20 amino acids and the position of the stop signals. The table emphasizes the importance of the central nucleotide in the codons and predicts that purines control the charge while pyrimidines determine the polarity of the amino acids. This prediction was experimentally tested.

@article{Biro2003408, abstract = {A periodic table of codons has been designed where the codons are in regular locations. The table has four fields (16 places in each) one with each of the four nucleotides (A, U, G, C) in the central codon position. Thus, AAA (lysine), UUU (phenylalanine), GGG (glycine), and CCC (proline) were placed into the corners of the fields as the main codons (and amino acids) of the fields. They were connected to each other by six axes. The resulting nucleic acid periodic table showed perfect axial symmetry for codons. The corresponding amino acid table also displaced periodicity regarding the biochemical properties (charge and hydropathy) of the 20 amino acids and the position of the stop signals. The table emphasizes the importance of the central nucleotide in the codons and predicts that purines control the charge while pyrimidines determine the polarity of the amino acids. This prediction was experimentally tested.}, added-at = {2009-02-08T21:16:11.000+0100}, author = {Biro, J. C. and Benyó, B. and Sansom, C. and Szlávecz, Á. and Fördös, G. and Micsik, T. and Benyó, Z.}, biburl = {https://www.bibsonomy.org/bibtex/2da6249ad187e058b5e136d88da2d7aeb/sidney}, doi = {DOI: 10.1016/S0006-291X(03)00974-4}, interhash = {224607262dc43f48500ed4be1b9cb25b}, intrahash = {da6249ad187e058b5e136d88da2d7aeb}, issn = {0006-291X}, journal = {Biochemical and Biophysical Research Communications}, keywords = {Amino_acid Charge Codon Genetic_code Hydrophobicity Nucleic_acid Periodic_table Polarity Protein Translation}, number = 2, pages = {408 - 415}, timestamp = {2009-02-08T21:16:11.000+0100}, title = {A common periodic table of codons and amino acids}, url = {http://dx.doi.org/10.1016/S0006-291X(03)00974-4}, volume = 306, year = 2003 }