The objective of this study was to characterize the antimicrobial resistance patterns of 100 clinical isolates of Enterobacter spp. with special regard to the occurrence of extended-spectrum beta-lactamases (ESBLs) and plasmid-mediated quinolone resistance by qnr-determinants. The rate of ESBL- and qnr-positive isolates was 7\% and 14\%, respectively. Thirteen isolates harbored a qnrA1, and a further isolate harbored a qnrB4 gene. Moreover, qnr-determinants were significantly associated with ESBL-expression. No carbapeneme or tigecycline resistance was detected in the collective tested. To conclude, these data confirm the increase of multiple antimicrobial resistance mechanisms in Enterobacter spp.
%0 Journal Article
%1 mueller_characterization_2011
%A Müller, Sophia
%A Oesterlein, Anett
%A Frosch, Matthias
%A Abele-Horn, Marianne
%A Valenza, Giuseppe
%D 2011
%J Microbial Drug Resistance (Larchmont, N.Y.)
%K ag_horn imported
%N 1
%P 99--103
%R 10.1089/mdr.2010.0114
%T Characterization of Extended-Spectrum Beta-Lactamases and qnr Plasmid-Mediated Quinolone Resistance in German Isolates of Enterobacter Species
%U http://www.ncbi.nlm.nih.gov/pubmed/21190474
%V 17
%X The objective of this study was to characterize the antimicrobial resistance patterns of 100 clinical isolates of Enterobacter spp. with special regard to the occurrence of extended-spectrum beta-lactamases (ESBLs) and plasmid-mediated quinolone resistance by qnr-determinants. The rate of ESBL- and qnr-positive isolates was 7\% and 14\%, respectively. Thirteen isolates harbored a qnrA1, and a further isolate harbored a qnrB4 gene. Moreover, qnr-determinants were significantly associated with ESBL-expression. No carbapeneme or tigecycline resistance was detected in the collective tested. To conclude, these data confirm the increase of multiple antimicrobial resistance mechanisms in Enterobacter spp.
@article{mueller_characterization_2011,
abstract = {The objective of this study was to characterize the antimicrobial resistance patterns of 100 clinical isolates of Enterobacter spp. with special regard to the occurrence of extended-spectrum beta-lactamases {(ESBLs)} and plasmid-mediated quinolone resistance by qnr-determinants. The rate of {ESBL-} and qnr-positive isolates was 7\% and 14\%, respectively. Thirteen isolates harbored a {qnrA1,} and a further isolate harbored a {qnrB4} gene. Moreover, qnr-determinants were significantly associated with {ESBL-expression.} No carbapeneme or tigecycline resistance was detected in the collective tested. To conclude, these data confirm the increase of multiple antimicrobial resistance mechanisms in Enterobacter spp.},
added-at = {2011-04-07T15:44:20.000+0200},
author = {Müller, Sophia and Oesterlein, Anett and Frosch, Matthias and {Abele-Horn}, Marianne and Valenza, Giuseppe},
biburl = {https://www.bibsonomy.org/bibtex/23109662b5a4a0f6969937ed2ab211aa4/hymi},
doi = {10.1089/mdr.2010.0114},
interhash = {46fb959cec277791f633eb1b6be53229},
intrahash = {3109662b5a4a0f6969937ed2ab211aa4},
issn = {1931-8448},
journal = {Microbial Drug Resistance {(Larchmont,} {N.Y.)}},
keywords = {ag_horn imported},
month = mar,
note = {{PMID:} 21190474},
number = 1,
pages = {99--103},
timestamp = {2011-04-07T15:47:41.000+0200},
title = {Characterization of {Extended-Spectrum} {Beta-Lactamases} and qnr {Plasmid-Mediated} Quinolone Resistance in German Isolates of Enterobacter Species},
url = {http://www.ncbi.nlm.nih.gov/pubmed/21190474},
volume = 17,
year = 2011
}