%0 Journal Article %1 muralidhara2021perturbations %A Muralidhara, P. %A Weiste, C. %A Collani, S. %A Krischke, M. %A Kreisz, P. %A Draken, J. %A Feil, R. %A Mair, A. %A Teige, M. %A Muller, M. J. %A Schmid, M. %A Becker, D. %A Lunn, J. E. %A Rolland, F. %A Hanson, J. %A Droge-Laser, W. %D 2021 %J Proc Natl Acad Sci U S A %K & Arabidopsis/genetics/*growth development/metabolism myOwn uni_network %N 37 %R 10.1073/pnas.2106961118 %T Perturbations in plant energy homeostasis prime lateral root initiation via SnRK1-bZIP63-ARF19 signaling %U https://www.ncbi.nlm.nih.gov/pubmed/34504003https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449399/pdf/pnas.202106961.pdf %V 118 %X Plants adjust their energy metabolism to continuous environmental fluctuations, resulting in a tremendous plasticity in their architecture. The regulatory circuits involved, however, remain largely unresolved. In Arabidopsis, moderate perturbations in photosynthetic activity, administered by short-term low light exposure or unexpected darkness, lead to increased lateral root (LR) initiation. Consistent with expression of low-energy markers, these treatments alter energy homeostasis and reduce sugar availability in roots. Here, we demonstrate that the LR response requires the metabolic stress sensor kinase Snf1-RELATED-KINASE1 (SnRK1), which phosphorylates the transcription factor BASIC LEUCINE ZIPPER63 (bZIP63) that directly binds and activates the promoter of AUXIN RESPONSE FACTOR19 (ARF19), a key regulator of LR initiation. Consistently, starvation-induced ARF19 transcription is impaired in bzip63 mutants. This study highlights a positive developmental function of SnRK1. During energy limitation, LRs are initiated and primed for outgrowth upon recovery. Hence, this study provides mechanistic insights into how energy shapes the agronomically important root system.

@article{muralidhara2021perturbations, abstract = {Plants adjust their energy metabolism to continuous environmental fluctuations, resulting in a tremendous plasticity in their architecture. The regulatory circuits involved, however, remain largely unresolved. In Arabidopsis, moderate perturbations in photosynthetic activity, administered by short-term low light exposure or unexpected darkness, lead to increased lateral root (LR) initiation. Consistent with expression of low-energy markers, these treatments alter energy homeostasis and reduce sugar availability in roots. Here, we demonstrate that the LR response requires the metabolic stress sensor kinase Snf1-RELATED-KINASE1 (SnRK1), which phosphorylates the transcription factor BASIC LEUCINE ZIPPER63 (bZIP63) that directly binds and activates the promoter of AUXIN RESPONSE FACTOR19 (ARF19), a key regulator of LR initiation. Consistently, starvation-induced ARF19 transcription is impaired in bzip63 mutants. This study highlights a positive developmental function of SnRK1. During energy limitation, LRs are initiated and primed for outgrowth upon recovery. Hence, this study provides mechanistic insights into how energy shapes the agronomically important root system.}, added-at = {2024-02-15T15:08:22.000+0100}, author = {Muralidhara, P. and Weiste, C. and Collani, S. and Krischke, M. and Kreisz, P. and Draken, J. and Feil, R. and Mair, A. and Teige, M. and Muller, M. J. and Schmid, M. and Becker, D. and Lunn, J. E. and Rolland, F. and Hanson, J. and Droge-Laser, W.}, biburl = {https://www.bibsonomy.org/bibtex/26be20aeeb3a9f600dbb4daeec16e3c2b/jvsi_all}, doi = {10.1073/pnas.2106961118}, interhash = {5afa59d9d3acf4fc70cb77fffe8e2c30}, intrahash = {6be20aeeb3a9f600dbb4daeec16e3c2b}, issn = {1091-6490 (Electronic) 0027-8424 (Print) 0027-8424 (Linking)}, journal = {Proc Natl Acad Sci U S A}, keywords = {& Arabidopsis/genetics/*growth development/metabolism myOwn uni_network}, note = {Muralidhara, Prathibha Weiste, Christoph Collani, Silvio Krischke, Markus Kreisz, Philipp Draken, Jan Feil, Regina Mair, Andrea Teige, Markus Muller, Martin J Schmid, Markus Becker, Dirk Lunn, John E Rolland, Filip Hanson, Johannes Droge-Laser, Wolfgang eng Research Support, Non-U.S. Gov't 2021/09/11 Proc Natl Acad Sci U S A. 2021 Sep 14;118(37):e2106961118. doi: 10.1073/pnas.2106961118.}, number = 37, timestamp = {2024-02-15T15:11:55.000+0100}, title = {Perturbations in plant energy homeostasis prime lateral root initiation via SnRK1-bZIP63-ARF19 signaling}, type = {Journal Article}, url = {https://www.ncbi.nlm.nih.gov/pubmed/34504003https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449399/pdf/pnas.202106961.pdf}, volume = 118, year = 2021 }