Genes that encode mitochondrial homologues to the bacterial enzymes of fatty acid synthesis were found in various eukaryotic species. Inactivation of these genes leads to a disturbed mitochondrial respiration and an increase in mitochondrial lysophospholipids. We postulate that there is a mitochondrial biosynthetic system providing fatty acids for phospholipid repair. The mitochondrial acyl carrier protein may also play another role, supporting the formation of the respiratory NADH:ubiquinone oxidoreductase.
%0 Journal Article
%1 Schneider1997a
%A Schneider, R.
%A Brors, B.
%A Massow, M.
%A Weiss, H.
%D 1997
%J FEBS Lett
%K 3-Oxoacyl-(Acyl-Carrier-Protein) Acids, Acyl Animals; Carrier Complex Consumption; Data; Dehydrogenase, Electron Fatty Humans; I; Mitochondria, Molecular NADH NADH, NADPH Oxidoreductases, Oxygen Phospholipids, Phylogeny; Protein, Sequence Symbiosis Synthase, Transport biosynthesis; genetics/metabolism; metabolism;
%N 3
%P 249--252
%T Mitochondrial fatty acid synthesis: a relic of endosymbiontic origin and a specialized means for respiration.
%V 407
%X Genes that encode mitochondrial homologues to the bacterial enzymes of fatty acid synthesis were found in various eukaryotic species. Inactivation of these genes leads to a disturbed mitochondrial respiration and an increase in mitochondrial lysophospholipids. We postulate that there is a mitochondrial biosynthetic system providing fatty acids for phospholipid repair. The mitochondrial acyl carrier protein may also play another role, supporting the formation of the respiratory NADH:ubiquinone oxidoreductase.
@article{Schneider1997a,
__markedentry = {[bbrors:6]},
abstract = {Genes that encode mitochondrial homologues to the bacterial enzymes of fatty acid synthesis were found in various eukaryotic species. Inactivation of these genes leads to a disturbed mitochondrial respiration and an increase in mitochondrial lysophospholipids. We postulate that there is a mitochondrial biosynthetic system providing fatty acids for phospholipid repair. The mitochondrial acyl carrier protein may also play another role, supporting the formation of the respiratory NADH:ubiquinone oxidoreductase.},
added-at = {2015-04-09T12:36:21.000+0200},
author = {Schneider, R. and Brors, B. and Massow, M. and Weiss, H.},
biburl = {https://www.bibsonomy.org/bibtex/2792efceda718b511ec33ebc751380e20/bbrors},
institution = {hneider@uni-duesseldorf.de},
interhash = {b6d77876b813c5019c0e593f183b4d18},
intrahash = {792efceda718b511ec33ebc751380e20},
journal = {FEBS Lett},
keywords = {3-Oxoacyl-(Acyl-Carrier-Protein) Acids, Acyl Animals; Carrier Complex Consumption; Data; Dehydrogenase, Electron Fatty Humans; I; Mitochondria, Molecular NADH NADH, NADPH Oxidoreductases, Oxygen Phospholipids, Phylogeny; Protein, Sequence Symbiosis Synthase, Transport biosynthesis; genetics/metabolism; metabolism;},
language = {eng},
medline-pst = {ppublish},
month = May,
number = 3,
owner = {bbrors},
pages = {249--252},
pii = {S0014-5793(97)00360-8},
pmid = {9175861},
timestamp = {2015-04-09T12:36:21.000+0200},
title = {Mitochondrial fatty acid synthesis: a relic of endosymbiontic origin and a specialized means for respiration.},
volume = 407,
year = 1997
}