US military physicians and researchers helped identify the optimum treatment dose of the naturally occurring compound quinine and collaborated with the pharmaceutical industry in the development and eventual US Food and Drug Administration approval of the synthetic antimalarial drugs chloroquine, primaquine, chloroquine-primaquine, sulfadoxine-pyrimethamine, mefloquine, doxycycline, halofantrine, and atovaquone-proguanil. Because malaria parasites develop drug resistance, the US military must continue to support the creation and testing of new drugs to prevent and treat malaria until an effective malaria vaccine is developed. New antimalarial drugs also benefit civilians residing in and traveling to malarious areas.
Description
Role of US Military Research Programs in the Development of US Food and Drug Administration–Approved Antimalarial Drugs | Clinical Infectious Diseases | Oxford Academic
%0 Journal Article
%1 kitchen2006military
%A Kitchen, Lynn W.
%A Vaughn, David W.
%A Skillman, Donald R.
%D 2006
%J Clinical Infectious Diseases
%K (h)cq US_military malaria
%N 1
%P 67-71
%R https://doi.org/10.1086/504873
%T Role of US Military Research Programs in the Development of US Food and Drug Administration–Approved Antimalarial Drugs
%U https://academic.oup.com/cid/article/43/1/67/310038
%V 43
%X US military physicians and researchers helped identify the optimum treatment dose of the naturally occurring compound quinine and collaborated with the pharmaceutical industry in the development and eventual US Food and Drug Administration approval of the synthetic antimalarial drugs chloroquine, primaquine, chloroquine-primaquine, sulfadoxine-pyrimethamine, mefloquine, doxycycline, halofantrine, and atovaquone-proguanil. Because malaria parasites develop drug resistance, the US military must continue to support the creation and testing of new drugs to prevent and treat malaria until an effective malaria vaccine is developed. New antimalarial drugs also benefit civilians residing in and traveling to malarious areas.
@article{kitchen2006military,
abstract = {US military physicians and researchers helped identify the optimum treatment dose of the naturally occurring compound quinine and collaborated with the pharmaceutical industry in the development and eventual US Food and Drug Administration approval of the synthetic antimalarial drugs chloroquine, primaquine, chloroquine-primaquine, sulfadoxine-pyrimethamine, mefloquine, doxycycline, halofantrine, and atovaquone-proguanil. Because malaria parasites develop drug resistance, the US military must continue to support the creation and testing of new drugs to prevent and treat malaria until an effective malaria vaccine is developed. New antimalarial drugs also benefit civilians residing in and traveling to malarious areas.},
added-at = {2020-04-30T17:10:32.000+0200},
author = {Kitchen, Lynn W. and Vaughn, David W. and Skillman, Donald R.},
biburl = {https://www.bibsonomy.org/bibtex/281d8c6ca845fffe49233688bcc7f2bd3/fordham1},
description = {Role of US Military Research Programs in the Development of US Food and Drug Administration–Approved Antimalarial Drugs | Clinical Infectious Diseases | Oxford Academic},
doi = {https://doi.org/10.1086/504873},
interhash = {18afd75a758c5410327d378554bdbc41},
intrahash = {81d8c6ca845fffe49233688bcc7f2bd3},
journal = {Clinical Infectious Diseases},
keywords = {(h)cq US_military malaria},
month = {July},
number = 1,
pages = {67-71},
timestamp = {2020-04-30T17:10:32.000+0200},
title = {Role of US Military Research Programs in the Development of US Food and Drug Administration–Approved Antimalarial Drugs},
url = {https://academic.oup.com/cid/article/43/1/67/310038},
volume = 43,
year = 2006
}