The Interplay of Thyroid Hormones, Body Mass Index, and Kidney Function in Wasit City: Implications for Metabolic Health
CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCE, 4 (5):
632-639 (September 2023)Abstract
The research discusses the challenges in assessing obesity in patients with Chronic Kidney Disease (CKD) and the limitations of using Body Mass Index (BMI) for this purpose. It also touches on the potential connection between BMI, particularly underweight, and kidney disease , use of urea and creatinine concentrations to evaluate renal function and mentions the common clinical presentations of kidney disease. Lastly, it notes the impact of CKD on thyroid hormone levels. To assess thyroid hormones (FT3, FT4 and TSH) in chronic renal failure (CRF) patients it included 50 patients, 29 were males and 21 were females and their age range from 20 to 60 years. The patient was diagnosed as having renal failure for both sex based on the history and clinical examination. The control groups were 30; they were collected from medical staff and relatives who were free from signs and symptoms of renal disease, lipid disorders, and thyroid hormones disorders. 20 were males and 10 were females, and their ages range from22 to 66 years. BMI has a positive significant correlation with gender , and it has a negative significant relationship with T4.TSH showed a significant negative correlation with T3 and T4 and a significant positive relationship with kidney failure Serum urea and creatinine concentrations in chronic renal failure (CRF) patients were found to be significantly high compared with control group (P<0.001).Serum FT3, FT4 and TSH concentrations in CRF patients were found to be no significantly lower compared with control group.