Tuberculosis Diagnostics with Modern Solutions (Literature Review)
CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCES, (2022)Abstract
Every year, 3 million people die of TB worldwide, and another 8 million fall ill. Over the past few years, domestic doctors have recorded an explosion of this disease in our camp. Every year the number of patients increases by 25-30% and, which is especially alarming, children and adolescents often become victims. Inflammatory processes are generally very similar regardless of their cause. Modern solutions have been emerging in the past decade, seeking to overcome many of the inhibiting issues in this field by utilising recent advances in molecular biology, genetics and sequencing or even completely ‘reinventing the wheel’, by developing novel and unprecedented diagnostic techniques. In this mini review, the issues and challenges arising from the historical methods of diagnosing tuberculosis are discussed, followed by outlaying their particular lack of appropriateness for regions of the world where tuberculosis still remains endemic. Subsequently, more recent developments of new methods and technological advancements as ‘modern weapons’ in the battle to defeat this disease and associated challenges are reviewed, and finally an outlook is presented, highlighting the future of the modern solutions under development, which are envisioned to lay the platform for improvements in delivering timely intervention, reduce immense expense and burden on healthcare systems worldwide, while saving millions of lives and eventually, may enable the eradication of this ancient disease.