Abstract

To clarify the neurodevelopmental outcome in children with intraventricular hemorrhage, a follow-up study was performed for a consecutive group of 335 subjects in one tertiary center born between 1981 and 1999. Their mean gestation and birth weight were 28.1 weeks and 1162.2 gm, respectively. The follow-up period ranged from 3 to 20 years (mean: 7.5 years). The neurodevelopmental outcomes were normal in 188 (56.1\%), cerebral palsy in 75 (22.4\%), mental retardation in 34 (10.2\%), and borderline intelligence in 38 (11.3\%). There were statistically significant differences in the outcomes among the groups with different grades of intraventricular hemorrhage. Approximately 70\% of the children with intraventricular hemorrhage grade 1 were normal, whereas only 15.4\% of the children with intraventricular hemorrhage grade 4 were normal. Cerebral palsy was associated with as high as 71.2\% in the patients with intraventricular hemorrhage grade 4. The overall incidence of epilepsy was 39/335 (11.6\%). This study has not demonstrated clear improvement of the outcome in children with intraventricular hemorrhage between the 1980s and 1990s.

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