%0 Book Section %1 mac %A Kharazmi, Arsalan %A Giwercman, Birgit %A Høiby, Niels %B Biofilms %D 1999 %E Doyle, Ron J. %I Academic Press %K masters %P 207 - 215 %R http://dx.doi.org/10.1016/S0076-6879(99)10018-1 %T Robbins device in biofilm research %U http://www.sciencedirect.com/science/article/pii/S0076687999100181 %V 310 %X Publisher Summary Typical studies compare the properties of adherent bacteria with those of the equivalent planktonic population of cells passing through the device. The Robbins device has been used extensively to investigate the immune response to biofilm-grown bacteria and antibiotic resistance. The technique has provided much valuable information on the physiology and metabolism of biofilm bacteria, regulation of various bacterial genes and their products, and resistance to antimicrobial compounds and their interactions with various components of the immune system. This chapter discusses the use of the Robbins device in infection-related biofilm research. Studies using the Robbins device indicate that bacteria persisting in biofilm mediate a constant low-grade activation of various parameters of the immune system, thereby protecting them from the harmful action of the immune system and, at the same time, contributing to the chronic inflammation and tissue damage in the lungs of cystic fibrosis patients infected with P. aeruginosa. The use of the Robbins device has contributed a great deal to the understanding of the mechanisms by which microorganisms protect themselves from the hostile environment in which they live.

@incollection{mac, abstract = {Publisher Summary Typical studies compare the properties of adherent bacteria with those of the equivalent planktonic population of cells passing through the device. The Robbins device has been used extensively to investigate the immune response to biofilm-grown bacteria and antibiotic resistance. The technique has provided much valuable information on the physiology and metabolism of biofilm bacteria, regulation of various bacterial genes and their products, and resistance to antimicrobial compounds and their interactions with various components of the immune system. This chapter discusses the use of the Robbins device in infection-related biofilm research. Studies using the Robbins device indicate that bacteria persisting in biofilm mediate a constant low-grade activation of various parameters of the immune system, thereby protecting them from the harmful action of the immune system and, at the same time, contributing to the chronic inflammation and tissue damage in the lungs of cystic fibrosis patients infected with P. aeruginosa. The use of the Robbins device has contributed a great deal to the understanding of the mechanisms by which microorganisms protect themselves from the hostile environment in which they live. }, added-at = {2015-03-19T12:59:46.000+0100}, author = {Kharazmi, Arsalan and Giwercman, Birgit and Høiby, Niels}, biburl = {https://www.bibsonomy.org/bibtex/2a7e7a85ba499d38b2bdac71823f59767/ross_mck}, booktitle = {Biofilms}, description = {[16] Robbins device in biofilm research}, doi = {http://dx.doi.org/10.1016/S0076-6879(99)10018-1}, editor = {Doyle, Ron J.}, interhash = {2e5e7ec94d1b141f86968be216869685}, intrahash = {a7e7a85ba499d38b2bdac71823f59767}, issn = {0076-6879}, keywords = {masters}, pages = {207 - 215}, publisher = {Academic Press}, series = {Methods in Enzymology }, timestamp = {2015-03-19T12:59:46.000+0100}, title = {Robbins device in biofilm research }, url = {http://www.sciencedirect.com/science/article/pii/S0076687999100181}, volume = 310, year = 1999 }