The structure and connectivity of the nervous system of the
nematode Caenorhabditis elegans has been deduced from
reconstructions of electron micrographs of serial
sections. The hermaphrodite nervous system has a total
complement of 302 neurons, which are arranged in an
essentially invariant structure. Neurons with similar
morphologies and connectivities have been grouped together
into classes; there are 118 such classes. Neurons have simple
morphologies with few, if any, branches. Processes from
neurons run in defined positions within bundles of parallel
processes, synaptic connections being made en passant. Process
bundles are arranged longitudinally and circumferentially and
are often adjacent to ridges of hypodermis. Neurons are
generally highly locally connected, making synaptic
connections with many of their neighbours. Muscle cells have
arms that run out to process bundles containing motoneuron
axons. Here they receive their synaptic input in defined
regions along the surface of the bundles, where motoneuron
axons reside. Most of the morphologically identifiable
synaptic connections in a typical animal are described. These
consist of about 5000 chemical synapses, 2000 neuromuscular
junctions and 600 gap junctions.
%0 Journal Article
%1 white_structure_1986
%A White, J. G.
%A Southgate, E.
%A Thomson, J. N.
%A Brenner, S.
%D 1986
%J Philosophical Transactions of the Royal Society of London. B, Biological Sciences
%K connectome
%N 1165
%P 1--340
%R 10.1098/rstb.1986.0056
%T The Structure of the Nervous System of the Nematode Caenorhabditis elegans
%U http://rstb.royalsocietypublishing.org/content/314/1165/1
%V 314
%X The structure and connectivity of the nervous system of the
nematode Caenorhabditis elegans has been deduced from
reconstructions of electron micrographs of serial
sections. The hermaphrodite nervous system has a total
complement of 302 neurons, which are arranged in an
essentially invariant structure. Neurons with similar
morphologies and connectivities have been grouped together
into classes; there are 118 such classes. Neurons have simple
morphologies with few, if any, branches. Processes from
neurons run in defined positions within bundles of parallel
processes, synaptic connections being made en passant. Process
bundles are arranged longitudinally and circumferentially and
are often adjacent to ridges of hypodermis. Neurons are
generally highly locally connected, making synaptic
connections with many of their neighbours. Muscle cells have
arms that run out to process bundles containing motoneuron
axons. Here they receive their synaptic input in defined
regions along the surface of the bundles, where motoneuron
axons reside. Most of the morphologically identifiable
synaptic connections in a typical animal are described. These
consist of about 5000 chemical synapses, 2000 neuromuscular
junctions and 600 gap junctions.
@article{white_structure_1986,
abstract = {The structure and connectivity of the nervous system of the
nematode Caenorhabditis elegans has been deduced from
reconstructions of electron micrographs of serial
sections. The hermaphrodite nervous system has a total
complement of 302 neurons, which are arranged in an
essentially invariant structure. Neurons with similar
morphologies and connectivities have been grouped together
into classes; there are 118 such classes. Neurons have simple
morphologies with few, if any, branches. Processes from
neurons run in defined positions within bundles of parallel
processes, synaptic connections being made en passant. Process
bundles are arranged longitudinally and circumferentially and
are often adjacent to ridges of hypodermis. Neurons are
generally highly locally connected, making synaptic
connections with many of their neighbours. Muscle cells have
arms that run out to process bundles containing motoneuron
axons. Here they receive their synaptic input in defined
regions along the surface of the bundles, where motoneuron
axons reside. Most of the morphologically identifiable
synaptic connections in a typical animal are described. These
consist of about 5000 chemical synapses, 2000 neuromuscular
junctions and 600 gap junctions.},
added-at = {2014-01-19T14:51:25.000+0100},
author = {White, J. G. and Southgate, E. and Thomson, J. N. and Brenner, S.},
bdsk-url-1 = {http://rstb.royalsocietypublishing.org/content/314/1165/1},
bdsk-url-2 = {http://dx.doi.org/10.1098/rstb.1986.0056},
biburl = {https://www.bibsonomy.org/bibtex/2b780268e794c41123d7f2e01492d894a/neurokernel},
doi = {10.1098/rstb.1986.0056},
interhash = {87d562d6903f2e865ec39d2ac6cfbaf9},
intrahash = {b780268e794c41123d7f2e01492d894a},
issn = {0962-8436, 1471-2970},
journal = {Philosophical Transactions of the Royal Society of London. B, Biological Sciences},
keywords = {connectome},
month = nov,
note = {{PMID:} 22462104},
number = 1165,
pages = {1--340},
timestamp = {2014-01-19T14:51:25.000+0100},
title = {The Structure of the Nervous System of the Nematode {Caenorhabditis elegans}},
url = {http://rstb.royalsocietypublishing.org/content/314/1165/1},
urldate = {2013-09-25},
volume = 314,
year = 1986
}