%0 Journal Article %1 Casci2011Dosage %A Casci, Tanita %D 2011 %I Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved. %J Nat Rev Genet %K dosage-compensation genetics %N 1 %P 2 %R 10.1038/nrg2921 %T Dosage compensation: What dosage compensation? %U http://dx.doi.org/10.1038/nrg2921 %V 12 %X According to a widely held view first proposed by Susumu Ohno, genes on the active mammalian X chromosome are expressed at twice the level of those present on two autosomes. A study using RNA–seq data overturns this model by showing that, in mice and humans, genes on the X chromosome are expressed at the same level as those on autosomes.

@article{Casci2011Dosage, abstract = {According to a widely held view first proposed by Susumu Ohno, genes on the active mammalian X chromosome are expressed at twice the level of those present on two autosomes. A study using {RNA}–seq data overturns this model by showing that, in mice and humans, genes on the X chromosome are expressed at the same level as those on autosomes.}, added-at = {2018-12-02T16:09:07.000+0100}, author = {Casci, Tanita}, biburl = {https://www.bibsonomy.org/bibtex/2c3e700995277485e3d242c22d7aa4365/karthikraman}, citeulike-article-id = {8351661}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/nrg2921}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/nrg2921}, day = 30, doi = {10.1038/nrg2921}, interhash = {bb68d2fe8e139086ea02e3c17b85817a}, intrahash = {c3e700995277485e3d242c22d7aa4365}, issn = {1471-0056}, journal = {Nat Rev Genet}, keywords = {dosage-compensation genetics}, month = jan, number = 1, pages = 2, posted-at = {2010-12-03 10:22:09}, priority = {2}, publisher = {Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.}, timestamp = {2018-12-02T16:09:07.000+0100}, title = {Dosage compensation: What dosage compensation?}, url = {http://dx.doi.org/10.1038/nrg2921}, volume = 12, year = 2011 }