Book,

Designing clinical research : an epidemiologic approach

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Lippincott Williams & Wilkins, Philadelphia, Fourth edition, (2013)

Abstract

The 4th edition of Designing Clinical Research (DCR-4) marks the 25th anniversary of our first edition. The book is the most widely used textbook on clinical research methods, with more than 130,000 copies sold. We designed it as a manual for clinical research in all its flavors: clinical trials, observational studies, translational science, patient-oriented research, behavioral science, and health services research. We used epidemiologic terms and principles, presenting advanced conceptual material in a practical and reader-friendly way, and suggesting common sense approaches to the many judgments involved in designing a study.

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