Angiogenesis, the formation of new blood vessels from pre--existing ones, is central for both normal development and homeostasis as well as in certain pathological conditions. The vascular endothelial growth factors (VEGFs) and their receptors are prime regulators of both physiological and pathological angiogenesis. The different VEGFs have overlapping but specific roles in controlling the growth of new blood vessels. The VEGF receptors transduce signals mediating endothelial cell proliferation, migration, organization into functional vessels and remodeling of the vessel network. In recent years, rapid progress has been made in understanding the receptor-ligand interactions that orchestrate the neovascularization process
%0 Journal Article
%1 Veikkola.1999
%A Veikkola, T.
%A Alitalo, K.
%D 1999
%J Semin.Cancer Biol.
%K A Animals Blood Endothelial Factor Factors Growth Humans Kinase Kinases Laboratories Lymphokines Neoplasms Neovascularization Pathologic Physiologic Protein-Tyrosine Receptor Receptors Research Vascular Vessels blood etiology physiology supply
%N 3
%P 211-220
%T VEGFs, receptors and angiogenesis
%U PM:10343072
%V 9
%X Angiogenesis, the formation of new blood vessels from pre--existing ones, is central for both normal development and homeostasis as well as in certain pathological conditions. The vascular endothelial growth factors (VEGFs) and their receptors are prime regulators of both physiological and pathological angiogenesis. The different VEGFs have overlapping but specific roles in controlling the growth of new blood vessels. The VEGF receptors transduce signals mediating endothelial cell proliferation, migration, organization into functional vessels and remodeling of the vessel network. In recent years, rapid progress has been made in understanding the receptor-ligand interactions that orchestrate the neovascularization process
@article{Veikkola.1999,
abstract = {Angiogenesis, the formation of new blood vessels from pre--existing ones, is central for both normal development and homeostasis as well as in certain pathological conditions. The vascular endothelial growth factors (VEGFs) and their receptors are prime regulators of both physiological and pathological angiogenesis. The different VEGFs have overlapping but specific roles in controlling the growth of new blood vessels. The VEGF receptors transduce signals mediating endothelial cell proliferation, migration, organization into functional vessels and remodeling of the vessel network. In recent years, rapid progress has been made in understanding the receptor-ligand interactions that orchestrate the neovascularization process},
added-at = {2010-02-05T11:28:39.000+0100},
author = {Veikkola, T. and Alitalo, K.},
biburl = {https://www.bibsonomy.org/bibtex/2ced98b07c2443d24d7f22675eeb52e82/kanefendt},
interhash = {a457331660e3afe6b6edc030c556f4bb},
intrahash = {ced98b07c2443d24d7f22675eeb52e82},
journal = {Semin.Cancer Biol.},
keywords = {A Animals Blood Endothelial Factor Factors Growth Humans Kinase Kinases Laboratories Lymphokines Neoplasms Neovascularization Pathologic Physiologic Protein-Tyrosine Receptor Receptors Research Vascular Vessels blood etiology physiology supply},
number = 3,
pages = {211-220},
timestamp = {2010-02-05T11:28:47.000+0100},
title = {VEGFs, receptors and angiogenesis},
url = {PM:10343072},
volume = 9,
year = 1999
}