Synapses exhibit diverse functional properties, and it seems
likely that these properties are specialized to perform
specific computations. The Drosophila antennal lobe provides a
useful experimental preparation for exploring the relationship
between synaptic physiology and neural computations. This
review summarizes recent progress in describing synaptic
properties in the Drosophila antennal lobe. These studies
reveal that several types of synapses in this circuit are
highly specialized, and that these specializations are in some
cases under tight regulatory control. These synaptic
specializations can be understood in terms of the
computational features they confer on the
circuit. Specifically, many of these properties appear to
promote odor detection when odor concentrations are low, while
promoting adaptive gain control when odor concentrations are
high.
%0 Journal Article
%1 wilson_understanding_2011
%A Wilson, Rachel I.
%D 2011
%J Current Opinion in Neurobiology
%K drosophila olfactory
%N 2
%P 254--260
%R 10.1016/j.conb.2011.03.002
%T Understanding the functional consequences of synaptic specialization: insight from the Drosophila antennal lo\
be
%U http://www.sciencedirect.com/science/article/pii/S0959438811000420
%V 21
%X Synapses exhibit diverse functional properties, and it seems
likely that these properties are specialized to perform
specific computations. The Drosophila antennal lobe provides a
useful experimental preparation for exploring the relationship
between synaptic physiology and neural computations. This
review summarizes recent progress in describing synaptic
properties in the Drosophila antennal lobe. These studies
reveal that several types of synapses in this circuit are
highly specialized, and that these specializations are in some
cases under tight regulatory control. These synaptic
specializations can be understood in terms of the
computational features they confer on the
circuit. Specifically, many of these properties appear to
promote odor detection when odor concentrations are low, while
promoting adaptive gain control when odor concentrations are
high.
@article{wilson_understanding_2011,
abstract = {Synapses exhibit diverse functional properties, and it seems
likely that these properties are specialized to perform
specific computations. The Drosophila antennal lobe provides a
useful experimental preparation for exploring the relationship
between synaptic physiology and neural computations. This
review summarizes recent progress in describing synaptic
properties in the Drosophila antennal lobe. These studies
reveal that several types of synapses in this circuit are
highly specialized, and that these specializations are in some
cases under tight regulatory control. These synaptic
specializations can be understood in terms of the
computational features they confer on the
circuit. Specifically, many of these properties appear to
promote odor detection when odor concentrations are low, while
promoting adaptive gain control when odor concentrations are
high.},
added-at = {2014-01-19T13:43:44.000+0100},
author = {Wilson, Rachel I.},
bdsk-url-1 = {http://www.sciencedirect.com/science/article/pii/S0959438811000420},
bdsk-url-2 = {http://dx.doi.org/10.1016/j.conb.2011.03.002},
biburl = {https://www.bibsonomy.org/bibtex/2d3eb29a15c1c695c6799ac74509c5043/neurokernel},
doi = {10.1016/j.conb.2011.03.002},
interhash = {c560c521c0554835a3c7da34416bbddf},
intrahash = {d3eb29a15c1c695c6799ac74509c5043},
issn = {0959-4388},
journal = {Current Opinion in Neurobiology},
keywords = {drosophila olfactory},
month = apr,
number = 2,
pages = {254--260},
shorttitle = {Understanding the functional consequences of synaptic specialization},
timestamp = {2014-01-19T13:43:44.000+0100},
title = {Understanding the functional consequences of synaptic specialization: insight from the {Drosophila} antennal lo\
be},
url = {http://www.sciencedirect.com/science/article/pii/S0959438811000420},
urldate = {2012-01-29},
volume = 21,
year = 2011
}