%0 Journal Article %1 RN258 %A Costantino, A.R. %A Schneider, M.G.M. %A Galdamez, A. %A Ocampo, R.A. %A Mandolesi, S.D. %A Koll, L.C. %D 2015 %I 2015 Elsevier Ltd. %J Tetrahedron-Asymmetry %K analogs, anhydrides carboxylic-acids, derivatives, dqcauchile esterification, esters, in-situ, inhibitors, integrase ligands, taddol, %N 23 %P 1341-1347 %R 10.1016/j.tetasy.2015.10.014 %T The Synthesis of C-2 Symmetry Diesters of (3r,4r)-Ttfol through a Green and Stereoselective (2r,3r)-Taddol Rearrangement %U /brokenurl#<Go to ISI>://WOS:000366070000005 %V 26 %X An efficient, green, and atom economic methodology for the stereoselective synthesis of C-2 symmetry (3R,4R)-TTFOL diester derivatives has been developed. The procedure occurs through a (2R,3R)-TADDOL dioxolane cleavage and rearrangement under mild conditions by its reaction with a carboxylic acid in the presence of TFAA/H3PO4 without the need for an inert atmosphere to give generally high yields.

@article{RN258, abstract = {An efficient, green, and atom economic methodology for the stereoselective synthesis of C-2 symmetry (3R,4R)-TTFOL diester derivatives has been developed. The procedure occurs through a (2R,3R)-TADDOL dioxolane cleavage and rearrangement under mild conditions by its reaction with a carboxylic acid in the presence of TFAA/H3PO4 without the need for an inert atmosphere to give generally high yields. }, added-at = {2019-12-04T03:57:35.000+0100}, author = {Costantino, A.R. and Schneider, M.G.M. and Galdamez, A. and Ocampo, R.A. and Mandolesi, S.D. and Koll, L.C.}, biburl = {https://www.bibsonomy.org/bibtex/2dba1a2a6fd448c7691006a8accf042ef/dqcauchile}, doi = {10.1016/j.tetasy.2015.10.014}, interhash = {50f3757aedce1e2560063211ce14e526}, intrahash = {dba1a2a6fd448c7691006a8accf042ef}, issn = {0957-4166}, journal = {Tetrahedron-Asymmetry}, keywords = {analogs, anhydrides carboxylic-acids, derivatives, dqcauchile esterification, esters, in-situ, inhibitors, integrase ligands, taddol,}, number = 23, pages = {1341-1347}, publisher = {2015 Elsevier Ltd.}, timestamp = {2019-12-04T03:58:17.000+0100}, title = {The Synthesis of C-2 Symmetry Diesters of (3r,4r)-Ttfol through a Green and Stereoselective (2r,3r)-Taddol Rearrangement}, type = {Journal Article}, url = {/brokenurl#<Go to ISI>://WOS:000366070000005}, volume = 26, year = 2015 }