Summary: Genome-scale metabolic models often lack annotations that would allow them to be used for further analysis. Previous efforts have focused on associating metabolites in the model with a cross reference, but this can be problematic if the reference is not freely available, multiple resources are used or the metabolite is added from a literature review. Associating each metabolite with chemical structure provides unambiguous identification of the components and a more detailed view of the metabolism. We have developed an open-source desktop application that simplifies the process of adding database cross references and chemical structures to genome-scale metabolic models. Annotated models can be exported to the Systems Biology Markup Language open interchange format.Availability: Source code, binaries, documentation and tutorials are freely available at http://johnmay.github.com/metingear. The application is implemented in Java with bundles available for MS Windows and Macintosh OS X.Contact: johnmay@ebi.ac.ukSupplementary information: Supplementary data are available at Bioinformatics online.
%0 Journal Article
%1 May2013Metingear
%A May, John W.
%A James, A. Gordon
%A Steinbeck, Christoph
%D 2013
%J Bioinformatics
%K genome-scale metabolic-networks reconstruction tool
%N 17
%P 2213--2215
%R 10.1093/bioinformatics/btt342
%T Metingear: a development environment for annotating genome-scale metabolic models
%U http://dx.doi.org/10.1093/bioinformatics/btt342
%V 29
%X Summary: Genome-scale metabolic models often lack annotations that would allow them to be used for further analysis. Previous efforts have focused on associating metabolites in the model with a cross reference, but this can be problematic if the reference is not freely available, multiple resources are used or the metabolite is added from a literature review. Associating each metabolite with chemical structure provides unambiguous identification of the components and a more detailed view of the metabolism. We have developed an open-source desktop application that simplifies the process of adding database cross references and chemical structures to genome-scale metabolic models. Annotated models can be exported to the Systems Biology Markup Language open interchange format.Availability: Source code, binaries, documentation and tutorials are freely available at http://johnmay.github.com/metingear. The application is implemented in Java with bundles available for MS Windows and Macintosh OS X.Contact: johnmay@ebi.ac.ukSupplementary information: Supplementary data are available at Bioinformatics online.
@article{May2013Metingear,
abstract = {Summary: Genome-scale metabolic models often lack annotations that would allow them to be used for further analysis. Previous efforts have focused on associating metabolites in the model with a cross reference, but this can be problematic if the reference is not freely available, multiple resources are used or the metabolite is added from a literature review. Associating each metabolite with chemical structure provides unambiguous identification of the components and a more detailed view of the metabolism. We have developed an open-source desktop application that simplifies the process of adding database cross references and chemical structures to genome-scale metabolic models. Annotated models can be exported to the Systems Biology Markup Language open interchange {format.Availability}: Source code, binaries, documentation and tutorials are freely available at http://johnmay.github.com/metingear. The application is implemented in Java with bundles available for {MS} Windows and Macintosh {OS} {X.Contact}: {johnmay@ebi.ac.ukSupplementary} information: Supplementary data are available at Bioinformatics online.},
added-at = {2018-12-02T16:09:07.000+0100},
author = {May, John W. and James, A. Gordon and Steinbeck, Christoph},
biburl = {https://www.bibsonomy.org/bibtex/2ea8088d60876a90d9d9a92465703a451/karthikraman},
citeulike-article-id = {12438114},
citeulike-linkout-0 = {http://dx.doi.org/10.1093/bioinformatics/btt342},
citeulike-linkout-1 = {http://bioinformatics.oxfordjournals.org/cgi/content/abstract/29/17/2213},
citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/23766418},
citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=23766418},
day = 1,
doi = {10.1093/bioinformatics/btt342},
interhash = {eef9123b6ffec21cc7c0efcdd9a5e09c},
intrahash = {ea8088d60876a90d9d9a92465703a451},
issn = {1367-4811},
journal = {Bioinformatics},
keywords = {genome-scale metabolic-networks reconstruction tool},
month = sep,
number = 17,
pages = {2213--2215},
pmid = {23766418},
posted-at = {2013-06-19 06:42:37},
priority = {2},
timestamp = {2018-12-02T16:09:07.000+0100},
title = {Metingear: a development environment for annotating genome-scale metabolic models},
url = {http://dx.doi.org/10.1093/bioinformatics/btt342},
volume = 29,
year = 2013
}