%0 Journal Article %1 thom2013chloroquine %A Thomé, Rodolfo %A Lopes, Stefanie Costa Pinto %A Costa, Fabio Trindade Maranhão %A Verinaud, Liana %D 2013 %J Immunology Letters %K antiviral covid-19 %N 1 %P 50 - 57 %R https://doi.org/10.1016/j.imlet.2013.07.004 %T Chloroquine: Modes of action of an undervalued drug %U http://www.sciencedirect.com/science/article/pii/S0165247813000965 %V 153 %X For more than two decades, chloroquine (CQ) was largely and deliberately used as first choice drug for malaria treatment. However, worldwide increasing cases of resistant strains of Plasmodium have hampered its use. Nevertheless, CQ has recently been tested as adjunct therapy in several inflammatory situations, such as rheumatoid arthritis and transplantation procedures, presenting intriguing and promising results. In this review, we discuss recent findings and CQ mechanisms of action vis-à-vis its use as a broad adjunct therapy.

@article{thom2013chloroquine, abstract = {For more than two decades, chloroquine (CQ) was largely and deliberately used as first choice drug for malaria treatment. However, worldwide increasing cases of resistant strains of Plasmodium have hampered its use. Nevertheless, CQ has recently been tested as adjunct therapy in several inflammatory situations, such as rheumatoid arthritis and transplantation procedures, presenting intriguing and promising results. In this review, we discuss recent findings and CQ mechanisms of action vis-à-vis its use as a broad adjunct therapy.}, added-at = {2020-08-08T18:22:48.000+0200}, author = {Thomé, Rodolfo and Lopes, Stefanie Costa Pinto and Costa, Fabio Trindade Maranhão and Verinaud, Liana}, biburl = {https://www.bibsonomy.org/bibtex/2fd5ccf70cbf365360f598496f02e7d9e/fordham1}, description = {Chloroquine: Modes of action of an undervalued drug - ScienceDirect}, doi = {https://doi.org/10.1016/j.imlet.2013.07.004}, interhash = {f5d488d4fd914eaf4527caafb2b528b8}, intrahash = {fd5ccf70cbf365360f598496f02e7d9e}, issn = {0165-2478}, journal = {Immunology Letters}, keywords = {antiviral covid-19}, note = {paywalled so no PDF available}, number = 1, pages = {50 - 57}, timestamp = {2020-08-08T18:22:48.000+0200}, title = {Chloroquine: Modes of action of an undervalued drug}, url = {http://www.sciencedirect.com/science/article/pii/S0165247813000965}, volume = 153, year = 2013 }