%0 Journal Article %1 cieslik2018cancer %A Cieślik, Marcin %A Chinnaiyan, Arul M. %D 2018 %J Nature Reviews Genetics %K clinical paywall review rna-seq shouldread %N 2 %P 93--109 %R 10.1038/nrg.2017.96 %T Cancer transcriptome profiling at the juncture of clinical translation %U https://doi.org/10.1038/nrg.2017.96 %V 19 %X RNA sequencing (RNA-seq) has the potential to bridge tumour genotypes (for example, mutations) and their phenotypic consequences (for example, cancer molecular subtypes).The field of transcriptomics has matured thanks to lockstep developments in experimental protocols, algorithms and databases.Methodological and algorithmic advances continue to enable clinical applications of transcriptome profiling.Detection of gene fusions is the most immediate application of RNA-seq.Gene expression signatures have demonstrated prognostic and predictive value.Transcriptome profiling will be essential for immuno-oncology.

@article{cieslik2018cancer, abstract = {RNA sequencing (RNA-seq) has the potential to bridge tumour genotypes (for example, mutations) and their phenotypic consequences (for example, cancer molecular subtypes).The field of transcriptomics has matured thanks to lockstep developments in experimental protocols, algorithms and databases.Methodological and algorithmic advances continue to enable clinical applications of transcriptome profiling.Detection of gene fusions is the most immediate application of RNA-seq.Gene expression signatures have demonstrated prognostic and predictive value.Transcriptome profiling will be essential for immuno-oncology.}, added-at = {2020-01-22T22:10:29.000+0100}, author = {Cieślik, Marcin and Chinnaiyan, Arul M.}, biburl = {https://www.bibsonomy.org/bibtex/2904f06d86a2a28bb3bdc9ea41549851d/marcsaric}, description = {Cancer transcriptome profiling at the juncture of clinical translation | Nature Reviews Genetics}, doi = {10.1038/nrg.2017.96}, interhash = {3a9960c2ecc3eb274cdf118474f37294}, intrahash = {904f06d86a2a28bb3bdc9ea41549851d}, issn = {14710064}, journal = {Nature Reviews Genetics}, keywords = {clinical paywall review rna-seq shouldread}, number = 2, pages = {93--109}, refid = {Cieślik2018}, timestamp = {2020-01-22T22:10:29.000+0100}, title = {Cancer transcriptome profiling at the juncture of clinical translation}, url = {https://doi.org/10.1038/nrg.2017.96}, volume = 19, year = 2018 }