Abstract
Much of the sophisticated chemistry of life is accomplished by multicomponent
complexes, which act as molecular machines. Intrinsic to their accuracy
and efficiency is the energy that is supplied by hydrolysis of nucleoside
triphosphates. Conditions that deplete energy sources should therefore
cause decay and death. But studies on organisms that are exposed
to prolonged stress indicate that this fate could be circumvented
through the formation of highly ordered intracellular assemblies.
In these thermodynamically stable structures, vital components are
protected by a physical sequestration that is independent of energy
consumption.
- 11823798
- adaptation,
- bacillus
- bacterial
- bacterial,
- biological,
- coli,
- computer-assisted,
- crystallization,
- damage,
- dna
- dna,
- dna-binding
- energy
- escherichia
- gov't,
- image
- metabolism,
- models,
- molecular,
- non-u.s.
- oxidative
- processing,
- protein
- proteins,
- repair,
- research
- ribosomes,
- secondary,
- spores,
- stress,
- structure,
- subtilis,
- superhelical,
- support,
- thermodynamics,
- tomography,
- viral,
- virion,
Users
Please
log in to take part in the discussion (add own reviews or comments).