%0 Journal Article %1 Clarac:1992p45367 %A Clarac, Francois %A el Manira, A %A Cattaert, Daniel %D 1992 %J Curr Op Neurobiol %K Action Activity, Afferent Animals, Astacoidea, Cats, Channel Channels, Chloride Electric GABA-A, GTP-Binding Gating, Ion Locomotion, Membrane Models: Motor Neurological, Pathways, Potentials, Proteins, Receptors: Sensation, Signal Stimulation, Synaptic Transduction Transmission, %N 6 %P 764--9 %T Presynaptic control as a mechanism of sensory-motor integration %V 2 %X In studies of central nervous system networks, it is synaptic transmission to the postsynaptic soma-dendritic membrane that has received the most attention, in particular in relation to the analysis of sensory-motor integration. Sensory transmission is gated during ongoing movements in both invertebrates and vertebrates, such that it may be depressed in one phase of a cyclic movement and facilitated in another, in order to optimize the execution of the ongoing motor task. This presynaptic modulation is not limited to sensory afferents, but also occurs in synapses of both excitatory and inhibitory premotor interneurons. The modulation can be mediated by the release of different transmitters at axo-axonal synapses, which activate different types of receptors. In addition, presynaptic sensory axons can be coupled via gap junctions, which under certain conditions may mediate a presynaptic facilitation.

@article{Clarac:1992p45367, abstract = {In studies of central nervous system networks, it is synaptic transmission to the postsynaptic soma-dendritic membrane that has received the most attention, in particular in relation to the analysis of sensory-motor integration. Sensory transmission is gated during ongoing movements in both invertebrates and vertebrates, such that it may be depressed in one phase of a cyclic movement and facilitated in another, in order to optimize the execution of the ongoing motor task. This presynaptic modulation is not limited to sensory afferents, but also occurs in synapses of both excitatory and inhibitory premotor interneurons. The modulation can be mediated by the release of different transmitters at axo-axonal synapses, which activate different types of receptors. In addition, presynaptic sensory axons can be coupled via gap junctions, which under certain conditions may mediate a presynaptic facilitation.}, added-at = {2009-11-12T16:21:13.000+0100}, affiliation = {CNRS, Marseille, France.}, author = {Clarac, Fran{\c c}ois and el Manira, A and Cattaert, Daniel}, biburl = {https://www.bibsonomy.org/bibtex/2f444d6b92a7ff7ea7012d9588f041d46/fdiehl}, date-added = {2009-09-23 23:13:03 +0200}, date-modified = {2009-11-10 09:44:42 +0100}, description = {bib-komplett}, interhash = {4a6496425b3f4bb4f4347bb9c37e38d4}, intrahash = {f444d6b92a7ff7ea7012d9588f041d46}, journal = {Curr Op Neurobiol}, keywords = {Action Activity, Afferent Animals, Astacoidea, Cats, Channel Channels, Chloride Electric GABA-A, GTP-Binding Gating, Ion Locomotion, Membrane Models: Motor Neurological, Pathways, Potentials, Proteins, Receptors: Sensation, Signal Stimulation, Synaptic Transduction Transmission,}, language = {eng}, local-url = {file://localhost/Neurobio/Papers/1335811.pdf}, month = Dec, number = 6, pages = {764--9}, pmid = {1335811}, rating = {0}, timestamp = {2009-11-12T16:21:24.000+0100}, title = {Presynaptic control as a mechanism of sensory-motor integration}, uri = {papers://7B65697B-E216-4648-8A41-C67830C0DC73/Paper/p45367}, volume = 2, year = 1992 }