Abstract
Novel pyrrolizidines (1) were synthesized from 1,3-dipolar cycloaddition
of azomethine ylides and dipolarophiles (4). The reactions were highly
diastereoselective and regioselective and were carried out under reflux
and ultrasonic condition at room temperature. In general, milder
conditions and moderate improvements in rates and reaction times were
observed when ultrasonic condition was used. The products were obtained
in high yields, and their structures were determined by H-1 and C-13 NMR
spectral data and X-ray diffraction. (c) 2007 Elsevier B.V. All rights
reserved.
Users
Please
log in to take part in the discussion (add own reviews or comments).