%0 Journal Article %1 kern2016discoal %A Kern, Andrew D. %A Schrider, Daniel R. %D 2016 %I Oxford University Press (OUP) %J Bioinformatics %K coalescent_theory selection simulation software %N 24 %P 3839--3841 %R 10.1093/bioinformatics/btw556 %T Discoal: flexible coalescent simulations with selection %U https://doi.org/10.1093%2Fbioinformatics%2Fbtw556 %V 32 %X Summary: Here we describe discoal, a coalescent simulator able to generate population samples that include selective sweeps in a feature-rich, flexible manner. discoal can perform simulations conditioning on the fixation of an allele due to drift or either hard or soft sweeps—even those occurring a large genetic distance away from the simulated locus. discoal can simulate sweeps with recurrent mutation to the adaptive allele, recombination, and gene conversion, under non-equilibrium demographic histories and without specifying an allele frequency trajectory in advance. Availability and Implementation: discoal is implemented in the C programming language. Source code is freely available on GitHub (https://github.com/kern-lab/discoal) under a GNU General Public License.

@article{kern2016discoal, abstract = {Summary: Here we describe discoal, a coalescent simulator able to generate population samples that include selective sweeps in a feature-rich, flexible manner. discoal can perform simulations conditioning on the fixation of an allele due to drift or either hard or soft sweeps—even those occurring a large genetic distance away from the simulated locus. discoal can simulate sweeps with recurrent mutation to the adaptive allele, recombination, and gene conversion, under non-equilibrium demographic histories and without specifying an allele frequency trajectory in advance. Availability and Implementation: discoal is implemented in the C programming language. Source code is freely available on GitHub (https://github.com/kern-lab/discoal) under a GNU General Public License.}, added-at = {2017-09-07T07:12:56.000+0200}, author = {Kern, Andrew D. and Schrider, Daniel R.}, biburl = {https://www.bibsonomy.org/bibtex/2525eb3f62018ecacf3e1671e4724d19d/peter.ralph}, doi = {10.1093/bioinformatics/btw556}, interhash = {590ecc000e2d5aa21d52c13ed700e118}, intrahash = {525eb3f62018ecacf3e1671e4724d19d}, journal = {Bioinformatics}, keywords = {coalescent_theory selection simulation software}, month = aug, number = 24, pages = {3839--3841}, publisher = {Oxford University Press ({OUP})}, timestamp = {2017-09-07T07:12:56.000+0200}, title = {Discoal: flexible coalescent simulations with selection}, url = {https://doi.org/10.1093%2Fbioinformatics%2Fbtw556}, volume = 32, year = 2016 }