%0 Journal Article %1 Menkes1994 %A Menkes, J. H. %A Curran, J. %D 1994 %J AJNR Am J Neuroradiol %K Adolescent; Adult; Asphyxia Neonatorum; Basal Ganglia Diseases; Brain; Cerebral Palsy; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Magnetic Resonance Imaging; Male %N 3 %P 451--457 %T Clinical and MR correlates in children with extrapyramidal cerebral palsy. %V 15 %X PURPOSE: To identify the characteristic MR findings in extrapyramidal cerebral palsy. METHOD: Six patients who had suffered intrapartum asphyxia and who subsequently developed extrapyramidal cerebral palsy were identified. Asphyxia was evidenced by severe neonatal systemic acidosis as documented by a venous cord pH of less than 7.0 whenever available, or acidosis in subsequent arterial blood gas samples, and clinical signs of an acute hypoxic-ischemic encephalopathy during the neonatal period. In addition, 1- and 5-minute Apgar scores were 3 or less, and there had been need for intubation or vigorous resuscitation in the delivery room. There were three boys and three girls, all born at term, with birth weight appropriate for gestational age, and without a history of bilirubin levels above 15 mg/dL. MR imaging at 1.5 T was performed between 1 and 19 years of age. RESULTS: In all subjects focal high signal abnormality was demonstrated in the posterior putamen and the anterior or posterior thalamus. There were no other findings in most cases. CONCLUSION: MR demonstrated lesions in the putamen and thalamus in all of our six patients with severe extrapyramidal cerebral palsy who had suffered intrapartum asphyxia.

@article{Menkes1994, abstract = {PURPOSE: To identify the characteristic MR findings in extrapyramidal cerebral palsy. METHOD: Six patients who had suffered intrapartum asphyxia and who subsequently developed extrapyramidal cerebral palsy were identified. Asphyxia was evidenced by severe neonatal systemic acidosis as documented by a venous cord pH of less than 7.0 whenever available, or acidosis in subsequent arterial blood gas samples, and clinical signs of an acute hypoxic-ischemic encephalopathy during the neonatal period. In addition, 1- and 5-minute Apgar scores were 3 or less, and there had been need for intubation or vigorous resuscitation in the delivery room. There were three boys and three girls, all born at term, with birth weight appropriate for gestational age, and without a history of bilirubin levels above 15 mg/dL. MR imaging at 1.5 T was performed between 1 and 19 years of age. RESULTS: In all subjects focal high signal abnormality was demonstrated in the posterior putamen and the anterior or posterior thalamus. There were no other findings in most cases. CONCLUSION: MR demonstrated lesions in the putamen and thalamus in all of our six patients with severe extrapyramidal cerebral palsy who had suffered intrapartum asphyxia.}, added-at = {2014-07-19T20:47:28.000+0200}, author = {Menkes, J. H. and Curran, J.}, biburl = {https://www.bibsonomy.org/bibtex/2be3d1e658d993a18985fd60c53eb902a/ar0berts}, groups = {public}, interhash = {5cb8e346a27cf61142e8e70f72a75753}, intrahash = {be3d1e658d993a18985fd60c53eb902a}, journal = {AJNR Am J Neuroradiol}, keywords = {Adolescent; Adult; Asphyxia Neonatorum; Basal Ganglia Diseases; Brain; Cerebral Palsy; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Magnetic Resonance Imaging; Male}, month = Mar, number = 3, pages = {451--457}, pmid = {8197940}, timestamp = {2014-07-19T20:47:28.000+0200}, title = {Clinical and MR correlates in children with extrapyramidal cerebral palsy.}, username = {ar0berts}, volume = 15, year = 1994 }