%0 Journal Article %1 noauthororeditor %A |, Gaziev Karim Umarovich %D 2023 %J CENTRAL ASIAN JOURNAL OF THEORETICAL AND APPLIED SCIENCE %K cholelithiasis, diseases, elderly endocrine parients %N 10 %P 185-190 %T Features of the Course of Cholelithis Disease in Elderly People with Diseases of the Internal Secretion Glands %U https://cajotas.centralasianstudies.org/index.php/CAJOTAS/article/view/1316/1371 %V 4 %X The number of patients with cholelithiasis and endocrine pathology increase at eldery age. The patient’s age over 60 years is one of the risk factors of complications after cholecystectomy. The aim of this study is to investigate the effect of endocrine disorders on immediate results of surgical treatment of elderly patients with cholelithiasis. Materials & methods. 295 patients with cholelithiasis were operated on: 107 (36.3%) patients over 60 years (main group) and 188 (63.7%) patients younger than 60 years (control group). Results & discussion. The correlation between the age of the patients and severity of gallbladder’s inflammation was determined (r=0.176; p=0.002). The choledocholithiasis was diagnosed in 14 (13.1%) cases in the main group and in seven (3.7%) cases in the control group (p=0.003). Endocrine disorders were indicated at elderly patients more often (81.3% vs 67.7%; p=0.011). Open and conversion operations were performed at patients over 60 years more often (30.8% vs 9.0%; p<0.001). 14 (13.1%) patients of the main group and six (3.2%) patients of control group had postoperative complications (p=0.001). The hospital stay of elderly patients was longer (Me=10.0 days vs Me=8.0 days; p<0.001). The following correlations of elderly patients were established: between severity of gallbladder’s inflammation and waist circumference (r=0.239; p=0.013), between severity of gallbladder’s inflammation and the level of glucose (r=0.218; p=0.024), between severity of gallbladder’s inflammation and concentration of calcium (r=- 0.450; p<0.001); between the rate of purulent-inflammatory postoperative complications and the level of thyrotropic hormone (r=0.273; p=0.008), between the rate of purulent-inflammatory postoperative complications and hyperglycemia (r=0.211; p=0.029), between the rate of purulentinflammatory postoperative complications and open cholecystectomy (r=0.235; p=0.015); between hospital stay and waist circumference (r=0.197; p=0.047), between hospital stay and concentration of thyrotropic hormone (r=0.304; p=0.010), thyrotropic hormone and the level of calcium (r=-0.250; p=0.022). Conclusion. The endocrine disorders complicate the course of cholelithiasis at elderly patients that is accompanied by the increase of rates of postoperative complications and hospital stay..

@article{noauthororeditor, abstract = {The number of patients with cholelithiasis and endocrine pathology increase at eldery age. The patient’s age over 60 years is one of the risk factors of complications after cholecystectomy. The aim of this study is to investigate the effect of endocrine disorders on immediate results of surgical treatment of elderly patients with cholelithiasis. Materials & methods. 295 patients with cholelithiasis were operated on: 107 (36.3%) patients over 60 years (main group) and 188 (63.7%) patients younger than 60 years (control group). Results & discussion. The correlation between the age of the patients and severity of gallbladder’s inflammation was determined (r=0.176; p=0.002). The choledocholithiasis was diagnosed in 14 (13.1%) cases in the main group and in seven (3.7%) cases in the control group (p=0.003). Endocrine disorders were indicated at elderly patients more often (81.3% vs 67.7%; p=0.011). Open and conversion operations were performed at patients over 60 years more often (30.8% vs 9.0%; p<0.001). 14 (13.1%) patients of the main group and six (3.2%) patients of control group had postoperative complications (p=0.001). The hospital stay of elderly patients was longer (Me=10.0 days vs Me=8.0 days; p<0.001). The following correlations of elderly patients were established: between severity of gallbladder’s inflammation and waist circumference (r=0.239; p=0.013), between severity of gallbladder’s inflammation and the level of glucose (r=0.218; p=0.024), between severity of gallbladder’s inflammation and concentration of calcium (r=- 0.450; p<0.001); between the rate of purulent-inflammatory postoperative complications and the level of thyrotropic hormone (r=0.273; p=0.008), between the rate of purulent-inflammatory postoperative complications and hyperglycemia (r=0.211; p=0.029), between the rate of purulentinflammatory postoperative complications and open cholecystectomy (r=0.235; p=0.015); between hospital stay and waist circumference (r=0.197; p=0.047), between hospital stay and concentration of thyrotropic hormone (r=0.304; p=0.010), thyrotropic hormone and the level of calcium (r=-0.250; p=0.022). Conclusion. The endocrine disorders complicate the course of cholelithiasis at elderly patients that is accompanied by the increase of rates of postoperative complications and hospital stay..}, added-at = {2024-03-06T10:08:24.000+0100}, author = {|, Gaziev Karim Umarovich}, biburl = {https://www.bibsonomy.org/bibtex/2606f6eb4eb4580c35c416a95636cb565/centralasian_20}, interhash = {6bae683dcf1eeba493afaa9c1d704844}, intrahash = {606f6eb4eb4580c35c416a95636cb565}, issn = {2660-5317}, journal = {CENTRAL ASIAN JOURNAL OF THEORETICAL AND APPLIED SCIENCE}, keywords = {cholelithiasis, diseases, elderly endocrine parients}, language = {english}, month = oct, number = 10, pages = {185-190}, timestamp = {2024-03-06T10:08:24.000+0100}, title = {Features of the Course of Cholelithis Disease in Elderly People with Diseases of the Internal Secretion Glands}, url = {https://cajotas.centralasianstudies.org/index.php/CAJOTAS/article/view/1316/1371}, volume = 4, year = 2023 }