Article,
Regulation of molecular dysfunction with Multi-Omics: A platform of personal care in diabetes syndrome
GSC Advanced Research and Reviews, 11 (2): 061–066 (May 2022)
DOI: 10.30574/gscarr.2022.11.2.0127
Abstract
The present early screening and analytic tests for diabetes mellitus depend on the changes in the amount of glucose in the blood and autoantibody detection. However, innovative techniques have changed medical research relevance (Diabetes included). For instance, the introduction of genotyping arrays supported large-scale genome-wide relations studies and methods for evaluating international transcripts level, leading to integrated genetics. Additionally, other omics techniques like proteomics and metabolomics are currently being included in biological researchers' daily practices. This short review provides a comprehensive analysis of such omics technologies and concentrates on methods for their incorporation across different omics layers. Unlike a single omics type, multi-omics offers the opportunity to acknowledge the flow of information that triggers the disease. The inclusion of omics as a molecular term means an all-inclusive or international evaluation of various molecules. Most of the multi-omics studies focus on type 2 diabetes. Moreover, medical advancements are also expected to increase the level of anticipation concerning type 2 diabetes. Most data are also being incorporated with treatment responses, thereby offering the needed advancements for precision medicine in type 2 diabetes, which is currently the most prevalent chronic illness experienced in both the developed and developing nations in equal measure.
