Article,
Genome-scale metabolic models of yeast, methods for their reconstruction, and other applications.
Methods in molecular biology (Clifton, N.J.), (2014)
Abstract
Here, we present the concept of genome-scale metabolic models and some of their applications in metabolic engineering of yeast and in the analysis of gene expression data. The yeast species for which there are available genome-scale metabolic models are reviewed, as well as the methods for the reconstruction of genome-scale metabolic models for new species. Some commonly used algorithms for metabolic engineering and data integration are described.
