%0 Journal Article %1 shetty_peritonitis_2005 %A Shetty, A K %A Nagaraj, S K %A Lorentz, W B %A Bitzan, M %D 2005 %J Infection %K Adolescent, Agents, Ceftriaxone, Cephalothin, Dialysis, Gentamicins, Glomerulonephritis, Humans, Infections, Injections, Intraperitoneal, Male, Neisseria Neisseriaceae Peritoneal Peritonitis mucosa, {Anti-Bacterial} {IGA,} %N 5-6 %P 390--392 %R 10.1007/s15010-005-5074-4 %T Peritonitis due to Neisseria mucosa in an adolescent receiving peritoneal dialysis %U http://www.ncbi.nlm.nih.gov/pubmed/16258875 %V 33 %X Neisseria mucosa is part of the normal nasopharyngeal flora and rarely pathogenic in humans. Reports of serious infections associated with this pathogen are very unusual. A 17-year-old boy with end-stage renal disease due to IgA nephropathy presented with acute, spontaneous, symptomatic peritoneal dialysis-associated peritonitis without reported break in sterility or PD catheter exit site infection. beta-lactamase-negative N. mucosa was isolated from the dialysate effluent. Intraperitoneal antibiotic treatment with cephalothin/gentamicin for 5 days and subsequent ceftriaxone led to complete resolution of the infection. This case demonstrates that "non-pathogenic" Neisseria species can cause clinically severe peritonitis with high intraperitoneal neutrophil counts, elevated C-reactive protein levels in the peritoneal effluent (in the presented case, 27,600/mul and 3.6 mg/l, respectively) and impaired peritoneal membrane transport function. To our knowledge, this is the first case of N. mucosa peritonitis complicating chronic peritoneal dialysis in an adolescent patient.

@article{shetty_peritonitis_2005, abstract = {Neisseria mucosa is part of the normal nasopharyngeal flora and rarely pathogenic in humans. Reports of serious infections associated with this pathogen are very unusual. A 17-year-old boy with end-stage renal disease due to {IgA} nephropathy presented with acute, spontaneous, symptomatic peritoneal dialysis-associated peritonitis without reported break in sterility or {PD} catheter exit site infection. beta-lactamase-negative N. mucosa was isolated from the dialysate effluent. Intraperitoneal antibiotic treatment with cephalothin/gentamicin for 5 days and subsequent ceftriaxone led to complete resolution of the infection. This case demonstrates that "non-pathogenic" Neisseria species can cause clinically severe peritonitis with high intraperitoneal neutrophil counts, elevated C-reactive protein levels in the peritoneal effluent (in the presented case, 27,600/mul and 3.6 mg/l, respectively) and impaired peritoneal membrane transport function. To our knowledge, this is the first case of N. mucosa peritonitis complicating chronic peritoneal dialysis in an adolescent patient.}, added-at = {2011-03-11T10:05:34.000+0100}, author = {Shetty, A K and Nagaraj, S K and Lorentz, W B and Bitzan, M}, biburl = {https://www.bibsonomy.org/bibtex/2580fdda6b111cd0b99a9f7066689fd4a/jelias}, doi = {10.1007/s15010-005-5074-4}, interhash = {75722078dc2415cf7b7664d7d456d315}, intrahash = {580fdda6b111cd0b99a9f7066689fd4a}, issn = {0300-8126}, journal = {Infection}, keywords = {Adolescent, Agents, Ceftriaxone, Cephalothin, Dialysis, Gentamicins, Glomerulonephritis, Humans, Infections, Injections, Intraperitoneal, Male, Neisseria Neisseriaceae Peritoneal Peritonitis mucosa, {Anti-Bacterial} {IGA,}}, month = oct, note = {{PMID:} 16258875}, number = {5-6}, pages = {390--392}, timestamp = {2011-03-11T10:05:39.000+0100}, title = {Peritonitis due to Neisseria mucosa in an adolescent receiving peritoneal dialysis}, url = {http://www.ncbi.nlm.nih.gov/pubmed/16258875}, volume = 33, year = 2005 }