%0 Journal Article %1 opella_nuclear_1976 %A Opella, S J %A Yesinowski, J P %A Waugh, J S %D 1976 %J Proc. Natl. Acad. Sci. U.S.A. %K Chemistry,Cholesterol,Magnetic Lipids,Motion,Physical,Physicochemical Phenomena,Pulmonary Resonance Spectroscopy,Membrane Surfactants,Temperature %N 11 %P 3812--3815 %T Nuclear magnetic resonance description of molecular motion and phase separations of cholesterol in lecithin dispersions %V 73 %X Proton-enhanced 13C nuclear magnetic resonance is used to obtain signals from labeled cholesterols in lecithin dispersions. The 26-(13)Ccholesterol resonance indicates that the aliphatic tail of the molecule undergoes reorientation fast enough to average completely the chemical shift anisotropy. In contrast, 4-(13)Ccholesterol signals are characteristic of limited anisotropic reorientation. The resonances from the 4 position are sensitive to the temperature-concentration phase diagram. A phase boundary is observed at about 20 mole percent cholesterol.

@article{opella_nuclear_1976, abstract = {Proton-enhanced 13C nuclear magnetic resonance is used to obtain signals from labeled cholesterols in lecithin dispersions. The [26-(13)C]cholesterol resonance indicates that the aliphatic tail of the molecule undergoes reorientation fast enough to average completely the chemical shift anisotropy. In contrast, [4-(13)C]cholesterol signals are characteristic of limited anisotropic reorientation. The resonances from the 4 position are sensitive to the temperature-concentration phase diagram. A phase boundary is observed at about 20 mole percent cholesterol.}, added-at = {2017-03-14T02:48:56.000+0100}, author = {Opella, S J and Yesinowski, J P and Waugh, J S}, biburl = {https://www.bibsonomy.org/bibtex/2c5cf945816c058edc70eb0d1dbd0d58f/nmrresource}, interhash = {78fd1c6ec145d39df5816a78f517bce5}, intrahash = {c5cf945816c058edc70eb0d1dbd0d58f}, issn = {0027-8424}, journal = {Proc. Natl. Acad. Sci. U.S.A.}, keywords = {Chemistry,Cholesterol,Magnetic Lipids,Motion,Physical,Physicochemical Phenomena,Pulmonary Resonance Spectroscopy,Membrane Surfactants,Temperature}, month = nov, number = 11, pages = {3812--3815}, pmid = {1069266}, timestamp = {2017-03-14T02:49:21.000+0100}, title = {{Nuclear magnetic resonance description of molecular motion and phase separations of cholesterol in lecithin dispersions}}, volume = 73, year = 1976 }