Abstract
Six new Cd(II) and Zn(II) macrocyclic Schiff base complexes from
cyclocondensation of 2,6-diacetylpyridine and three different liner
aromatic amines have been investigated. The resulting ligands, L-1 and
L-2 are 17- and L-3 18-membered pentaaza macrocycles. The complexes have
been characterized by a variety of methods such as IR, elemental
analysis, EI-Mass and conductivity measurements and in the case of
cadmium complex by H-1 and C-13 NMR spectroscopy. The crystal structure
of CdL1(CH3OH)(ClO4)(2) has been determined. In this complex, the
Cd(II) ion is coordinated to five nitrogen donor atoms of the ligand and
one oxygen atom from methanol in a N5O environment. The geometry around
the cadmium can be better described as in a slightly distorted
pentagonal-pyramidal. The synthesized compounds have antibacterial
activity against the three gram-positive bacteria: S. aureus, B. cereus
and C. xerosis, and also against the three gram-negative bacteria: E.
coli, K. pneumoniae and P. vulgaris. The results show that the
antibacterial activity of cadmium complexes is greater than that of zinc
complexes.
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