%0 Journal Article %1 Hugenholtz1988 %A Hugenholtz, H. %A Humphreys, P. %A McIntyre, W. M. %A Spasoff, R. A. %A Steel, K. %D 1988 %J Neurosurgery %K Adolescent; Cerebral Palsy; Child; Double-Blind Method; Electric Stimulation T; Female; Humans; Male; Muscle Spasticity; Prospective Studies; Spinal Cord; herapy %N 4 %P 707--714 %T Cervical spinal cord stimulation for spasticity in cerebral palsy. %V 22 %X A prospective double-blind study of high cervical spinal cord stimulation conducted in eight moderately disabled, spastic, cerebral palsied children failed to demonstrate any significant improvement over base line function during chronic spinal cord stimulation at either optimal stimulation parameters or random placebo parameters. Chronic stimulation included 4 consecutive months of stimulation for 24 hours each day. Stimulators were randomly programmed at optimal parameters for 2 of the 4 months and at placebo parameters for the remaining 2 months. At the end of each month of chronic stimulation, subjects were assessed with a multidisciplinary test battery that included a self-assessment, specific clinical examinations, tests of gross and fine motor control, neuropsychological and neurophysiological tests, a detailed gait analysis, and video recordings. By 6 months after the completion of the study, only 1 of the 8 subjects continued to use his stimulator on a regular basis, with minimal benefit.

@article{Hugenholtz1988, abstract = {A prospective double-blind study of high cervical spinal cord stimulation conducted in eight moderately disabled, spastic, cerebral palsied children failed to demonstrate any significant improvement over base line function during chronic spinal cord stimulation at either optimal stimulation parameters or random placebo parameters. Chronic stimulation included 4 consecutive months of stimulation for 24 hours each day. Stimulators were randomly programmed at optimal parameters for 2 of the 4 months and at placebo parameters for the remaining 2 months. At the end of each month of chronic stimulation, subjects were assessed with a multidisciplinary test battery that included a self-assessment, specific clinical examinations, tests of gross and fine motor control, neuropsychological and neurophysiological tests, a detailed gait analysis, and video recordings. By 6 months after the completion of the study, only 1 of the 8 subjects continued to use his stimulator on a regular basis, with minimal benefit.}, added-at = {2014-07-19T20:28:48.000+0200}, author = {Hugenholtz, H. and Humphreys, P. and McIntyre, W. M. and Spasoff, R. A. and Steel, K.}, biburl = {https://www.bibsonomy.org/bibtex/24d84a886f1822ef53d59ada3aab492e0/ar0berts}, groups = {public}, interhash = {7fbed441877a5ee7d4cc6ea5b4af28e8}, intrahash = {4d84a886f1822ef53d59ada3aab492e0}, journal = {Neurosurgery}, keywords = {Adolescent; Cerebral Palsy; Child; Double-Blind Method; Electric Stimulation T; Female; Humans; Male; Muscle Spasticity; Prospective Studies; Spinal Cord; herapy}, month = Apr, number = 4, pages = {707--714}, pmid = {3259683}, timestamp = {2014-07-19T20:28:48.000+0200}, title = {Cervical spinal cord stimulation for spasticity in cerebral palsy.}, username = {ar0berts}, volume = 22, year = 1988 }