%0 Journal Article %1 paulose2019spatial %A Paulose, Jayson %A Hermisson, Joachim %A Hallatschek, Oskar %D 2019 %I Public Library of Science %J PLOS Genetics %K long_distance_dispersal parallel_adaptation soft_sweeps %N 2 %P 1-29 %R 10.1371/journal.pgen.1007936 %T Spatial soft sweeps: Patterns of adaptation in populations with long-range dispersal %U https://doi.org/10.1371/journal.pgen.1007936 %V 15 %X Author summary When a species is spread out over a large geographic range, different regions may adapt to the same selection pressure by acquiring distinct beneficial mutations. The resulting pattern of genetic variation in the population is called a soft sweep. Dispersal strongly influences soft sweep patterns, as it determines how a mutation that arose in one region might spread to others. Although most plant and animal populations experience some amount of dispersal over very long distances, the impact of such long-range dispersal events on soft sweep patterns remains poorly understood. We use computer simulations and mathematical analysis to study patterns of genetic variation in a model of soft sweeps including long-range dispersal. We show that long-range dispersal leaves distinct signatures in the genetic makeup of the population, which can be detected in genetic samples from individuals across the range. Our results are important for correctly interpreting patterns of genetic diversity in populations that have undergone recent adaptation.

@article{paulose2019spatial, abstract = {Author summary When a species is spread out over a large geographic range, different regions may adapt to the same selection pressure by acquiring distinct beneficial mutations. The resulting pattern of genetic variation in the population is called a soft sweep. Dispersal strongly influences soft sweep patterns, as it determines how a mutation that arose in one region might spread to others. Although most plant and animal populations experience some amount of dispersal over very long distances, the impact of such long-range dispersal events on soft sweep patterns remains poorly understood. We use computer simulations and mathematical analysis to study patterns of genetic variation in a model of soft sweeps including long-range dispersal. We show that long-range dispersal leaves distinct signatures in the genetic makeup of the population, which can be detected in genetic samples from individuals across the range. Our results are important for correctly interpreting patterns of genetic diversity in populations that have undergone recent adaptation.}, added-at = {2020-03-01T20:13:07.000+0100}, author = {Paulose, Jayson and Hermisson, Joachim and Hallatschek, Oskar}, biburl = {https://www.bibsonomy.org/bibtex/2b647e338ac2d4a73f040efb609f8234f/peter.ralph}, doi = {10.1371/journal.pgen.1007936}, interhash = {acba348633f161063dcdfd2dddb966d1}, intrahash = {b647e338ac2d4a73f040efb609f8234f}, journal = {PLOS Genetics}, keywords = {long_distance_dispersal parallel_adaptation soft_sweeps}, month = {02}, number = 2, pages = {1-29}, publisher = {Public Library of Science}, timestamp = {2023-07-06T01:37:48.000+0200}, title = {Spatial soft sweeps: Patterns of adaptation in populations with long-range dispersal}, url = {https://doi.org/10.1371/journal.pgen.1007936}, volume = 15, year = 2019 }