%0 Journal Article %1 Poo2003 %A P?o, P. %A L?pez-Casas, J. A. %A Galv?n-Manso, M. %A Aquino-Fari?a, L. %A Terricabras-Carol, L. %A Campistol, J. %D 2003 %J Rev Neurol %K Botulinum Toxin Type A; Cerebral Palsy; Humans; Muscle Spasticity; Neuromuscular Agents; Treatment Outcome %N 1 %P 74--80 %T Botulinum toxin Type A. Indications and results %V 37 %X INTRODUCTION: Since introduction for clinical in the 80s, the botulinum toxin type A is being used with effectiveness in the treatment of different disorders that goes with exaggerated muscular activity. Numerous studies have been demonstrated useful for focal treatment of spasticity. PATIENTS AND METHODS: Some indications of the botulinum toxin type A for the treatment of the cerebral palsy are reviewed, emphasizing that it use must be in a global planning. The positive results and adverse events are reviewed, of a series of 278 patients with spastic cerebral palsy. RESULTS: 19\% of these patients have had a slightly positive answer, with modification of the tone but without functional repercussion, 49\% have had a moderate answer, 17.5\% have a good improvement and a 5\% have presented good improvement for a long time. Of 224 patients with more than a year of evolution, the 9.5\% have presented adverse reactions, but they have always been slight and transient. CONCLUSION: The botulinum toxin type A can be considered effective and safe for the treatment of spasticity, whenever the indication is correct and it is accompanied by a treatment of physiotherapy well oriented.

@article{Poo2003, abstract = {INTRODUCTION: Since introduction for clinical in the 80s, the botulinum toxin type A is being used with effectiveness in the treatment of different disorders that goes with exaggerated muscular activity. Numerous studies have been demonstrated useful for focal treatment of spasticity. PATIENTS AND METHODS: Some indications of the botulinum toxin type A for the treatment of the cerebral palsy are reviewed, emphasizing that it use must be in a global planning. The positive results and adverse events are reviewed, of a series of 278 patients with spastic cerebral palsy. RESULTS: 19\% of these patients have had a slightly positive answer, with modification of the tone but without functional repercussion, 49\% have had a moderate answer, 17.5\% have a good improvement and a 5\% have presented good improvement for a long time. Of 224 patients with more than a year of evolution, the 9.5\% have presented adverse reactions, but they have always been slight and transient. CONCLUSION: The botulinum toxin type A can be considered effective and safe for the treatment of spasticity, whenever the indication is correct and it is accompanied by a treatment of physiotherapy well oriented.}, added-at = {2014-07-19T20:58:13.000+0200}, author = {P?o, P. and L?pez-Casas, J. A. and Galv?n-Manso, M. and Aquino-Fari?a, L. and Terricabras-Carol, L. and Campistol, J.}, biburl = {https://www.bibsonomy.org/bibtex/26fc5ca15a8d9469bebdc54c63acc3b39/ar0berts}, groups = {public}, interhash = {af4ee07c022753f014e87ceda7a2a512}, intrahash = {6fc5ca15a8d9469bebdc54c63acc3b39}, journal = {Rev Neurol}, keywords = {Botulinum Toxin Type A; Cerebral Palsy; Humans; Muscle Spasticity; Neuromuscular Agents; Treatment Outcome}, number = 1, pages = {74--80}, pii = {rn2003221}, pmid = {12861515}, timestamp = {2014-07-19T20:58:13.000+0200}, title = {[Botulinum toxin Type A. Indications and results]}, username = {ar0berts}, volume = 37, year = 2003 }