Abstract
Between 1930 and 1975 biochemical and structural analysis of enzymes
led to a clear set of ideas that might form a basis for detailed
understanding of enzyme action. Further development required energetic
and thermodynamic analysis of enzymes in an aqueous medium, beyond
the computational power then available. Structural enzymology advanced
in other directions, but the fundamental questions of enzyme action
must soon be re-opened.
Users
Please
log in to take part in the discussion (add own reviews or comments).