%0 Journal Article %1 Meberg1996 %A Meberg, A. %A Broch, H. %D 1996 %J Tidsskr Nor Laegeforen %K Cerebral Palsy; Cohort Studies; History, 20th Century; Humans; Incidence; Infant Mortality; Infant, Newborn; Premature, Diseases; Intensive Care, Neonatal; Norway; Prognosis; Quality Assurance, Health Care %N 26 %P 3118--3123 %T A changing panorama of cerebral palsy? A population-based study of children born during the 20-year period 1970-89 %V 116 %X In a population-based study cerebral palsy was diagnosed in 110 cases (2.4 per 1,000) among live born children with birth weight > or = 500 g (N = 45,976) during the 20-year period 1970-89 (cerebral palsy cases with a postneonatal etiology excluded). The incidence of cerebral palsy showed a linear declining trend from 2.8 per 1,000 in the first five-year cohort born 1970-74 to 2.0 per 1,000 in children born 1985-89 (p = 0.17). 15.9\% of the decline in incidence of cerebral palsy from the first to the second ten-year cohort could be explained by a decreasing rate of low birth weight (500-2,499 g) in the population, from 4.2\% 1970-79 to 3.8\% 1980-89 (p < 0.05). The neonatal mortality rate declined significantly from 7.2 per 1,000 in the first to 3.9 per 1,000 in the last ten-year cohort respectively (p < 0.01). More children with cerebral palsy born in the ten-year period 1980-89 were treated with mechanical ventilation in the neonatal period (13/46; 28.3\%) than such children born in the ten-year period 1970-79 (4/64; 6.3\%) (p < 0.01). The results contrast with the traditional findings of a higher incidence of cerebral palsy incidence following improved survival of infants with low birth weight. Our results may reflect a more integrated development of perinatal care. Research on ways of preventing low birth weight may allow us to lower the incidence of cerebral palsy still further.

@article{Meberg1996, abstract = {In a population-based study cerebral palsy was diagnosed in 110 cases (2.4 per 1,000) among live born children with birth weight > or = 500 g (N = 45,976) during the 20-year period 1970-89 (cerebral palsy cases with a postneonatal etiology excluded). The incidence of cerebral palsy showed a linear declining trend from 2.8 per 1,000 in the first five-year cohort born 1970-74 to 2.0 per 1,000 in children born 1985-89 (p = 0.17). 15.9\% of the decline in incidence of cerebral palsy from the first to the second ten-year cohort could be explained by a decreasing rate of low birth weight (500-2,499 g) in the population, from 4.2\% 1970-79 to 3.8\% 1980-89 (p < 0.05). The neonatal mortality rate declined significantly from 7.2 per 1,000 in the first to 3.9 per 1,000 in the last ten-year cohort respectively (p < 0.01). More children with cerebral palsy born in the ten-year period 1980-89 were treated with mechanical ventilation in the neonatal period (13/46; 28.3\%) than such children born in the ten-year period 1970-79 (4/64; 6.3\%) (p < 0.01). The results contrast with the traditional findings of a higher incidence of cerebral palsy incidence following improved survival of infants with low birth weight. Our results may reflect a more integrated development of perinatal care. Research on ways of preventing low birth weight may allow us to lower the incidence of cerebral palsy still further.}, added-at = {2014-07-19T20:47:17.000+0200}, author = {Meberg, A. and Broch, H.}, biburl = {https://www.bibsonomy.org/bibtex/2545d9dd7c4d98c19bdec8f048ca5ac2e/ar0berts}, groups = {public}, interhash = {b749f21e88a19b603eca32995e6e5ac9}, intrahash = {545d9dd7c4d98c19bdec8f048ca5ac2e}, journal = {Tidsskr Nor Laegeforen}, keywords = {Cerebral Palsy; Cohort Studies; History, 20th Century; Humans; Incidence; Infant Mortality; Infant, Newborn; Premature, Diseases; Intensive Care, Neonatal; Norway; Prognosis; Quality Assurance, Health Care}, month = Oct, number = 26, pages = {3118--3123}, pmid = {8999573}, timestamp = {2014-07-19T20:47:17.000+0200}, title = {[A changing panorama of cerebral palsy? A population-based study of children born during the 20-year period 1970-89]}, username = {ar0berts}, volume = 116, year = 1996 }