%0 Journal Article %1 Dojat2000 %A Dojat, M %A Harf, A %A Touchard, D %A Lemaire, F %A Brochard, L %D 2000 %J Am J Respir Crit Care Med %K kbs ventilation %N 4 Pt 1 %P 1161-1166 %T Clinical evaluation of a computer-controlled pressure support mode %U http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737132/ %V 161 %X We have designed a computerized system providing closed-loop control of the level of pressure support ventilation (PSV). The system sets itself at the lowest level of PSV that maintains respiratory rate (RR), tidal volume (VT), and end-tidal CO(2) pressure (PET(CO(2))) within predetermined ranges defining acceptable ventilation (i.e., 12 300 ml > 250 if weight < 55 kg, and PET(CO(2)) < 55 mm Hg < 65 mm Hg if chronic CO(2) retention). Ten patients received computer-controlled (automatic) PSV and physician-controlled (standard) PSV, in random order, during 24 h for each mode. An estimation of occlusion pressure (P(0.1)) was recorded continuously. The average time spent with acceptable ventilation as previously defined was 66 +/- 24% of the total ventilation time with standard PSV versus 93 +/- 8% with automatic PSV (p < 0.05), whereas the level of PSV was similar during the two periods (17 +/- 4 cm H(2)O versus 19 +/- 6 cm H(2)O). The time spent with an estimated P(0.1) above 4 cm H(2)O was 34 +/- 35% of the standard PSV time versus only 11 +/- 17% of the automatic PSV time (p < 0.01). Automatic PSV increased the time spent within desired ventilation parameter ranges and apparently reduced periods of excessive workload.

@article{Dojat2000, abstract = {We have designed a computerized system providing closed-loop control of the level of pressure support ventilation (PSV). The system sets itself at the lowest level of PSV that maintains respiratory rate (RR), tidal volume (VT), and end-tidal CO(2) pressure (PET(CO(2))) within predetermined ranges defining acceptable ventilation (i.e., 12 300 ml [> 250 if weight < 55 kg], and PET(CO(2)) < 55 mm Hg [< 65 mm Hg if chronic CO(2) retention]). Ten patients received computer-controlled (automatic) PSV and physician-controlled (standard) PSV, in random order, during 24 h for each mode. An estimation of occlusion pressure (P(0.1)) was recorded continuously. The average time spent with acceptable ventilation as previously defined was 66 +/- 24% of the total ventilation time with standard PSV versus 93 +/- 8% with automatic PSV (p < 0.05), whereas the level of PSV was similar during the two periods (17 +/- 4 cm H(2)O versus 19 +/- 6 cm H(2)O). The time spent with an estimated P(0.1) above 4 cm H(2)O was 34 +/- 35% of the standard PSV time versus only 11 +/- 17% of the automatic PSV time (p < 0.01). Automatic PSV increased the time spent within desired ventilation parameter ranges and apparently reduced periods of excessive workload.}, added-at = {2012-02-15T09:22:33.000+0100}, author = {Dojat, M and Harf, A and Touchard, D and Lemaire, F and Brochard, L}, biburl = {https://www.bibsonomy.org/bibtex/2b6a96c467f99d933d535a1daf3b9151f/rhatko}, description = {Clinical evaluation of a computer-controlled pressure support mode}, groups = {public}, interhash = {bd29ac3c51d42245b10dad4c7194c5fc}, intrahash = {b6a96c467f99d933d535a1daf3b9151f}, journal = {Am J Respir Crit Care Med}, keywords = {kbs ventilation}, month = {April}, number = {4 Pt 1}, pages = {1161-1166}, pmid = {10764306}, timestamp = {2012-12-06T10:42:48.000+0100}, title = {Clinical evaluation of a computer-controlled pressure support mode}, url = {http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737132/}, username = {rhatko}, volume = 161, year = 2000 }