%0 Journal Article %1 vera_exploration_2009 %A Vera, Julio %A Kwon, Taesoo %A Schmitz, Ulf %A Kolch, Walter %D 2009 %J International Journal of Bioinformatics Research and Applications %K Binding Biology, Computational Dimerization, Humans, Multimerization, Protein Proteins Rostock SBI Sites, %N 4 %P 447--457 %T Exploration of homodimer receptor: homodimer protein interactions %U http://www.ncbi.nlm.nih.gov/pubmed/19640831 %V 5 %X Homodimerisation is producing a protein?protein complex composed of two identical molecules. Dimerisation is a phenomenon often occurring in the regulation of biochemical systems like signal transduction pathways. We investigated whether the existence of a homodimer-activated receptor and the activation of homodimer transducers correspond to a more general pattern in cell signalling. We developed a workflow to merge data from the Gene Ontology and the BIND database to produce a list of interactions between homodimer receptors and homodimer proteins. Finally, we found a prevalence of homodimer-homodimer interactions in signalling systems in human cells.

@article{vera_exploration_2009, abstract = {Homodimerisation is producing a protein?protein complex composed of two identical molecules. Dimerisation is a phenomenon often occurring in the regulation of biochemical systems like signal transduction pathways. We investigated whether the existence of a homodimer-activated receptor and the activation of homodimer transducers correspond to a more general pattern in cell signalling. We developed a workflow to merge data from the Gene Ontology and the {BIND} database to produce a list of interactions between homodimer receptors and homodimer proteins. Finally, we found a prevalence of homodimer-homodimer interactions in signalling systems in human cells.}, added-at = {2010-09-17T16:55:15.000+0200}, author = {Vera, Julio and Kwon, Taesoo and Schmitz, Ulf and Kolch, Walter}, biburl = {https://www.bibsonomy.org/bibtex/23a99c55cfdd9b439ecd72c69a04629a0/ra1602}, interhash = {cc96b842df08f7d6885b31e4248e37dc}, intrahash = {3a99c55cfdd9b439ecd72c69a04629a0}, issn = {1744-5485}, journal = {International Journal of Bioinformatics Research and Applications}, keywords = {Binding Biology, Computational Dimerization, Humans, Multimerization, Protein Proteins Rostock SBI Sites,}, note = {{PMID:} 19640831}, number = 4, pages = {447--457}, shorttitle = {Exploration of homodimer receptor}, timestamp = {2010-09-17T16:55:28.000+0200}, title = {Exploration of homodimer receptor: homodimer protein interactions}, url = {http://www.ncbi.nlm.nih.gov/pubmed/19640831}, volume = 5, year = 2009 }