Article,

Neuronal Ca$^2+$ signalling takes the local route.

, and .
Curr. Opin. Neurobiol., 2 (3): 302--307 (June 1992)

Abstract

The past year has seen several sets of experimental results demonstrate that fast, large and highly localized rises in intracellular Ca$^2+$ concentration can occur in neurons. These results confirm previous theoretical predictions of acute spatial compartmentalization of Ca$^2+$ signalling, and document a form of signalling that may occur whenever rapid and local signal processing is the goal. The dimensions involved present severe challenges for attempts to directly measure these signalling events.

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