Article,

Evaluation of Malondialdehyde (MDA) and Lipid Profile in Iraqi Pregnancy Women with Hypertension in Thi-Qar Governorate

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CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCE, 4 (5): 255-264 (September 2023)

Abstract

Objectives: Pregnant women with hypertension were studied to determine if their lipid profiles changed. It is well known that altered lipid profiles are associated with essential hypertension. This is because oxidative stress and weakened antioxidant defense can lead to free radical-induced membrane lipid peroxidation and potentially damage the vascular endothelium. Methods: For this research, we had one hundred expecting mothers split into two groups—one of 50 mums-to-be dealing with hypertension and the other serving as a control set. All of our participants spent 8 to 10 hours fasting prior to us collecting a blood sample from them. We then took note of their triglyceride levels, cholesterol readings, HDL, LDL, and the amount of MDA in their system. Results: Some telling differences arose when comparing a control group to the patient group. The patient cohort had higher TCH, TG, and VLDL than their counterparts. That said, LDL levels were the same for both groups. At the same time, HDL levels were lower in the patient set. whereas, MDA levels remained indistinguishable between the two groups. Conclusion: It's been expected that mamas with hypertension are more likely to see their lipid peroxidation levels rise and be confronted with cardiovascular disease later in life. The evidence? High TC, LDL, TG, VLDL, and MDA concentrations are present in the bloodstream.

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