%0 Book Section %1 statphys23_0716 %A Heermann, D.W. %A Bohn, M. %A Diesinger, P.M. %B Abstract Book of the XXIII IUPAP International Conference on Statistical Physics %C Genova, Italy %D 2007 %E Pietronero, Luciano %E Loreto, Vittorio %E Zapperi, Stefano %K biophysics distance dna genomic polymer statphys23 topic-10 %T Structural Organization and Properties of DNA in the Cell %U http://st23.statphys23.org/webservices/abstract/preview_pop.php?ID_PAPER=716 %X The dynamical architecture of the cell nucleus can be regarded as one of the grand challenges of structural biophysics. The genomic DNA and the histone proteins compacting it into chromatin account for the major part of the contents of the nucleus. We will discuss the structural properties of the DNA. We present a model for the chain that can successfully describe experimentally measured distance distributions on chromosome 1 and 11 in human cells using the notion of “ridge” regions (cluster of strongly expressed genes) and the “antiridge” regions.

@incollection{statphys23_0716, abstract = {The dynamical architecture of the cell nucleus can be regarded as one of the grand challenges of structural biophysics. The genomic DNA and the histone proteins compacting it into chromatin account for the major part of the contents of the nucleus. We will discuss the structural properties of the DNA. We present a model for the chain that can successfully describe experimentally measured distance distributions on chromosome 1 and 11 in human cells using the notion of “ridge” regions (cluster of strongly expressed genes) and the “antiridge” regions.}, added-at = {2007-06-20T10:16:09.000+0200}, address = {Genova, Italy}, author = {Heermann, D.W. and Bohn, M. and Diesinger, P.M.}, biburl = {https://www.bibsonomy.org/bibtex/2c9909ce42f6b5a716cfdefa8a77d4697/statphys23}, booktitle = {Abstract Book of the XXIII IUPAP International Conference on Statistical Physics}, editor = {Pietronero, Luciano and Loreto, Vittorio and Zapperi, Stefano}, interhash = {d39ad7aeb5b8d157c7de84ee8acb5941}, intrahash = {c9909ce42f6b5a716cfdefa8a77d4697}, keywords = {biophysics distance dna genomic polymer statphys23 topic-10}, month = {9-13 July}, timestamp = {2007-06-20T10:16:27.000+0200}, title = {Structural Organization and Properties of DNA in the Cell}, url = {http://st23.statphys23.org/webservices/abstract/preview_pop.php?ID_PAPER=716}, year = 2007 }