%0 Journal Article %1 Kleine_Kleffmann_2023 %A Kleine-Kleffmann, Lara %A Stepanenko, Vladimir %A Shoyama, Kazutaka %A Wehner, Marius %A Würthner, Frank %D 2023 %I American Chemical Society (ACS) %J J. Am. Chem. Soc. %K myown %R 10.1021/jacs.3c01002 %T Controlling the Supramolecular Polymerization of Squaraine Dyes by a Molecular Chaperone Analogue %U https://doi.org/10.1021%2Fjacs.3c01002 %X Molecular chaperones are proteins that assist in the (un)folding and (dis)assembly of other macromolecular structures toward their biologically functional state in a non-covalent manner. Transferring this concept from nature to artificial self-assembly processes, here, we show a new strategy to control supramolecular polymerization via a chaperone-like two-component system. A new kinetic trapping method was developed that enables efficient retardation of the spontaneous self-assembly of a squaraine dye monomer. The suppression of supramolecular polymerization could be regulated with a cofactor, which precisely initiates self-assembly. The presented system was investigated and characterized by ultraviolet–visible, Fourier transform infrared, and nuclear magnetic resonance spectroscopy, atomic force microscopy, isothermal titration calorimetry, and single-crystal X-ray diffraction. With these results, living supramolecular polymerization and block copolymer fabrication could be realized, demonstrating a new possibility for effective control over supramolecular polymerization processes.

@article{Kleine_Kleffmann_2023, abstract = {Molecular chaperones are proteins that assist in the (un)folding and (dis)assembly of other macromolecular structures toward their biologically functional state in a non-covalent manner. Transferring this concept from nature to artificial self-assembly processes, here, we show a new strategy to control supramolecular polymerization via a chaperone-like two-component system. A new kinetic trapping method was developed that enables efficient retardation of the spontaneous self-assembly of a squaraine dye monomer. The suppression of supramolecular polymerization could be regulated with a cofactor, which precisely initiates self-assembly. The presented system was investigated and characterized by ultraviolet–visible, Fourier transform infrared, and nuclear magnetic resonance spectroscopy, atomic force microscopy, isothermal titration calorimetry, and single-crystal X-ray diffraction. With these results, living supramolecular polymerization and block copolymer fabrication could be realized, demonstrating a new possibility for effective control over supramolecular polymerization processes.}, added-at = {2023-04-26T09:46:08.000+0200}, author = {Kleine-Kleffmann, Lara and Stepanenko, Vladimir and Shoyama, Kazutaka and Wehner, Marius and Würthner, Frank}, biburl = {https://www.bibsonomy.org/bibtex/20e9b841d44b4d3f7a189b618dd7e250b/wuerthner_group}, doi = {10.1021/jacs.3c01002}, interhash = {e466d98b44c57488cf5ffe1e4ba201cd}, intrahash = {0e9b841d44b4d3f7a189b618dd7e250b}, journal = {J. Am. Chem. Soc.}, keywords = {myown}, month = apr, publisher = {American Chemical Society ({ACS})}, timestamp = {2023-04-26T09:46:08.000+0200}, title = {Controlling the Supramolecular Polymerization of Squaraine Dyes by a Molecular Chaperone Analogue}, url = {https://doi.org/10.1021%2Fjacs.3c01002}, year = 2023 }