%0 Journal Article %1 Wess.2010 %A Wess, Christian %A Sarnthein, Johannes %A Krayenbühl, Niklaus %A Scholz, Markus %A Kunze, Ekkehard %A Meixensberger, Jürgen %D 2010 %J Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology %K Adult Aged Electric_Stimulation/methods Electrodes Electroencephalography/methods Evoked_Potentials,_Somatosensory/physiology Feasibility_Studies Female Humans Male Middle_Aged Monitoring,_Intraoperative Predictive_Value_of_Tests Reaction_Time/physiology Spectrum_Analysis/methods Subarachnoid_Hemorrhage/physiopathology/surgery Tibial_Nerve/physiopathology %N 12 %P 2172–2176 %T Spectral iEEG markers precede SSEP events during surgery for subarachnoid hemorrhage %V 121 %X OBJECTIVE\r\nDuring neurosurgical intracranial vascular manipulations, surgeons need early feed-back on the effects of temporary vascular occlusion. In surgical practice, commonly the amplitude of somatosensory evoked potentials (SSEP) is monitored. However, the latency between an ischemic event and the drop of SSEP amplitude may amount to several minutes. Therefore intracranial electroencephalogram (iEEG) is tested for its predictive value.\r\nMETHODS\r\nDuring surgery in 13 patients, SSEP was recorded simultaneously with iEEG. iEEG was analyzed real-time in the frequency domain. Spectral observables of the iEEG were validated on the basis of SSEP by computing the statistical correlation first for the whole data set, then for salient events occurring in the SSEP in the group of patients, and finally for salient events occurring in single patients.\r\nRESULTS\r\nPlacement of subdural strip electrodes was compatible with standard surgical routine. Maximal correlation between time series of iEEG and SSEP was found for relative alpha power, which preceded the drop of SSEP by 7min.\r\nCONCLUSIONS\r\niEEG is feasible during neurosurgical intracranial vascular manipulations. Monitoring relative alpha power detects salient events earlier than SSEP.\r\nSIGNIFICANCE\r\nEarly detection of salient events facilitates early reaction of the surgeon and may thereby aid to further reduce intraoperative morbidity.

@article{Wess.2010, abstract = {OBJECTIVE\r\nDuring neurosurgical intracranial vascular manipulations, surgeons need early feed-back on the effects of temporary vascular occlusion. In surgical practice, commonly the amplitude of somatosensory evoked potentials (SSEP) is monitored. However, the latency between an ischemic event and the drop of SSEP amplitude may amount to several minutes. Therefore intracranial electroencephalogram (iEEG) is tested for its predictive value.\r\nMETHODS\r\nDuring surgery in 13 patients, SSEP was recorded simultaneously with iEEG. iEEG was analyzed real-time in the frequency domain. Spectral observables of the iEEG were validated on the basis of SSEP by computing the statistical correlation first for the whole data set, then for salient events occurring in the SSEP in the group of patients, and finally for salient events occurring in single patients.\r\nRESULTS\r\nPlacement of subdural strip electrodes was compatible with standard surgical routine. Maximal correlation between time series of iEEG and SSEP was found for relative alpha power, which preceded the drop of SSEP by 7min.\r\nCONCLUSIONS\r\niEEG is feasible during neurosurgical intracranial vascular manipulations. Monitoring relative alpha power detects salient events earlier than SSEP.\r\nSIGNIFICANCE\r\nEarly detection of salient events facilitates early reaction of the surgeon and may thereby aid to further reduce intraoperative morbidity.}, added-at = {2014-10-14T15:28:15.000+0200}, author = {Wess, Christian and Sarnthein, Johannes and Krayenbühl, Niklaus and Scholz, Markus and Kunze, Ekkehard and Meixensberger, Jürgen}, biburl = {https://www.bibsonomy.org/bibtex/218c0aa18d61f73cac336863825ad9a80/drtester}, interhash = {eaa97d6919267727ba861ceb289264ed}, intrahash = {18c0aa18d61f73cac336863825ad9a80}, journal = {Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology}, keywords = {Adult Aged Electric_Stimulation/methods Electrodes Electroencephalography/methods Evoked_Potentials,_Somatosensory/physiology Feasibility_Studies Female Humans Male Middle_Aged Monitoring,_Intraoperative Predictive_Value_of_Tests Reaction_Time/physiology Spectrum_Analysis/methods Subarachnoid_Hemorrhage/physiopathology/surgery Tibial_Nerve/physiopathology}, number = 12, pages = {2172–2176}, timestamp = {2014-10-14T15:28:15.000+0200}, title = {Spectral iEEG markers precede SSEP events during surgery for subarachnoid hemorrhage}, volume = 121, year = 2010 }