%0 Journal Article %1 WOS:000343125400030 %A Oliveira, J I N %A Albuquerque, E L %A Fulco, U L %A Mauriz, P W %A Sarmento, R G %A Caetano, E W S %A Freire, V N %C TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND %D 2014 %I IOP PUBLISHING LTD %J EPL %K imported %N 6 %R 10.1209/0295-5075/107/68006 %T Conductance of single microRNAs chains related to the autism spectrum disorder %V 107 %X The charge transport properties of single-stranded microRNAs (miRNAs) chains associated to autism disorder were investigated. The computations were performed within a tight-binding model, together with a transfer matrix technique, with ionization energies and hopping parameters obtained by quantum chemistry method. Current-voltage (I x V) curves of twelve miRNA chains related to the autism spectrum disorders were calculated and analysed. We have obtained both semiconductor and insulator behavior, and a relationship between the current intensity and the autism-related miRNA bases sequencies, suggesting that a kind of electronic biosensor can be developed to distinguish different profiles of autism disorders. Copyright (C) EPLA, 2014

@article{WOS:000343125400030, abstract = {The charge transport properties of single-stranded microRNAs (miRNAs) chains associated to autism disorder were investigated. The computations were performed within a tight-binding model, together with a transfer matrix technique, with ionization energies and hopping parameters obtained by quantum chemistry method. Current-voltage (I x V) curves of twelve miRNA chains related to the autism spectrum disorders were calculated and analysed. We have obtained both semiconductor and insulator behavior, and a relationship between the current intensity and the autism-related miRNA bases sequencies, suggesting that a kind of electronic biosensor can be developed to distinguish different profiles of autism disorders. Copyright (C) EPLA, 2014}, added-at = {2022-05-23T20:00:14.000+0200}, address = {TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND}, author = {Oliveira, J I N and Albuquerque, E L and Fulco, U L and Mauriz, P W and Sarmento, R G and Caetano, E W S and Freire, V N}, biburl = {https://www.bibsonomy.org/bibtex/26478f5652a43fd41b9530b07523f93b0/ppgfis_ufc_br}, doi = {10.1209/0295-5075/107/68006}, interhash = {ec14ed2d8ab576887e3420a6a49907fa}, intrahash = {6478f5652a43fd41b9530b07523f93b0}, issn = {0295-5075}, journal = {EPL}, keywords = {imported}, number = 6, publisher = {IOP PUBLISHING LTD}, pubstate = {published}, timestamp = {2022-05-23T20:00:14.000+0200}, title = {Conductance of single microRNAs chains related to the autism spectrum disorder}, tppubtype = {article}, volume = 107, year = 2014 }